Identity
HGNC
LOCATION
14q11.2
LOCUSID
ALIAS
CDC68,FACTP140,SPT16,SPT16/CDC68
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 11198
MIM: 605012
HGNC: 11465
Ensembl: ENSG00000092201
Variants:
dbSNP: 11198
ClinVar: 11198
TCGA: ENSG00000092201
COSMIC: SUPT16H
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000092201 | ENST00000216297 | Q9Y5B9 |
| ENSG00000092201 | ENST00000555943 | G3V2X0 |
| ENSG00000092201 | ENST00000556309 | G3V5A4 |
| ENSG00000092201 | ENST00000557652 | G3V401 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36255738 | 2023 | The fly homolog of SUPT16H, a gene associated with neurodevelopmental disorders, is required in a cell-autonomous fashion for cell survival. | 5 |
| 36769360 | 2023 | Supt16 Haploinsufficiency Impairs PI3K/AKT/mTOR/Autophagy Pathway in Human Pluripotent Stem Cells Derived Neural Stem Cells. | 1 |
| 36801613 | 2023 | Structural basis for H2A-H2B recognitions by human Spt16. | 1 |
| 36255738 | 2023 | The fly homolog of SUPT16H, a gene associated with neurodevelopmental disorders, is required in a cell-autonomous fashion for cell survival. | 5 |
| 36769360 | 2023 | Supt16 Haploinsufficiency Impairs PI3K/AKT/mTOR/Autophagy Pathway in Human Pluripotent Stem Cells Derived Neural Stem Cells. | 1 |
| 36801613 | 2023 | Structural basis for H2A-H2B recognitions by human Spt16. | 1 |
| 35904816 | 2022 | FACT subunit SUPT16H associates with BRD4 and contributes to silencing of interferon signaling. | 5 |
| 36577379 | 2022 | Human FACT subunits coordinate to catalyze both disassembly and reassembly of nucleosomes. | 5 |
| 35904816 | 2022 | FACT subunit SUPT16H associates with BRD4 and contributes to silencing of interferon signaling. | 5 |
| 36577379 | 2022 | Human FACT subunits coordinate to catalyze both disassembly and reassembly of nucleosomes. | 5 |
| 33526453 | 2021 | Proteasomal Regulation of Mammalian SPT16 in Controlling Transcription. | 4 |
| 33526453 | 2021 | Proteasomal Regulation of Mammalian SPT16 in Controlling Transcription. | 4 |
| 31775157 | 2020 | FACT caught in the act of manipulating the nucleosome. | 96 |
| 31823155 | 2020 | Neurodevelopmental phenotype associated with CHD8-SUPT16H duplication. | 4 |
| 31924697 | 2020 | De novo variants in SUPT16H cause neurodevelopmental disorders associated with corpus callosum abnormalities. | 6 |
Citation
Dessen P
SUPT16H (SPT16 homolog, facilitates chromatin remodeling subunit)
Atlas Genet Cytogenet Oncol Haematol. 2008-07-01
Online version: http://atlasgeneticsoncology.org/gene/50177/supt16h
