ZMIZ1 (zinc finger MIZ-type containing 1)

2008-07-01  

Identity

HGNC
ZMIZ1
LOCATION
10q22.3
LOCUSID
57178
ALIAS
MIZ,NEDDFSA,RAI17,TRAFIP10,ZIMP10
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 57178
MIM: 607159
HGNC: 16493
Ensembl: ENSG00000108175

Variants:

dbSNP: 57178
ClinVar: 57178
TCGA: ENSG00000108175
COSMIC: ZMIZ1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000108175ENST00000334512Q9ULJ6
ENSG00000108175ENST00000446377F6WR09
ENSG00000108175ENST00000611351A0A087WYE6

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
381174362024Clinical report and genetic analysis of a novel variant in ZMIZ1 causing neurodevelopmental disorder with dysmorphic factors and distal skeletal anomalies in a Chinese family.0
381174542024Decreased ZMIZ1 suppresses melanogenesis in vitiligo by regulating mTOR/AKT/GSK-3β-mediated glucose uptake.1
383323462024Knockdown of circZMIZ1 enhances the anti-tumor activity of CD8(+) T cells to alleviate hepatocellular carcinoma.0
387180952024Zmiz1 is a novel regulator of lymphatic endothelial cell gene expression and function.2
388668282024Targeting the ZMIZ1-Notch1 signaling axis for the treatment of tongue squamous cell carcinoma.0
381174362024Clinical report and genetic analysis of a novel variant in ZMIZ1 causing neurodevelopmental disorder with dysmorphic factors and distal skeletal anomalies in a Chinese family.0
381174542024Decreased ZMIZ1 suppresses melanogenesis in vitiligo by regulating mTOR/AKT/GSK-3β-mediated glucose uptake.1
383323462024Knockdown of circZMIZ1 enhances the anti-tumor activity of CD8(+) T cells to alleviate hepatocellular carcinoma.0
387180952024Zmiz1 is a novel regulator of lymphatic endothelial cell gene expression and function.2
388668282024Targeting the ZMIZ1-Notch1 signaling axis for the treatment of tongue squamous cell carcinoma.0
345083032022Long non-coding RNA ZMIZ1-AS1 promotes osteosarcoma progression by stabilization of ZMIZ1.8
363070472022Zmiz1 is required for mature β-cell function and mass expansion upon high fat feeding.5
345083032022Long non-coding RNA ZMIZ1-AS1 promotes osteosarcoma progression by stabilization of ZMIZ1.8
363070472022Zmiz1 is required for mature β-cell function and mass expansion upon high fat feeding.5
346809782021Compound Heterozygote of Point Mutation and Chromosomal Microdeletion Involving OTUD6B Coinciding with ZMIZ1 Variant in Syndromic Intellectual Disability.6

Citation

Dessen P

ZMIZ1 (zinc finger MIZ-type containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2008-07-01

Online version: http://atlasgeneticsoncology.org/gene/50211