Identity
HGNC
LOCATION
2p16.1
LOCUSID
ALIAS
APE,GIRDIN,GIV,GRDN,HkRP1,KIAA1212,PEHO,PEHOL
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55704
MIM: 609736
HGNC: 25523
Ensembl: ENSG00000115355
Variants:
dbSNP: 55704
ClinVar: 55704
TCGA: ENSG00000115355
COSMIC: CCDC88A
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37923359 | 2024 | Integrins regulate hERG1 dynamics by girdin-dependent Gαi3: signaling and modeling in cancer cells. | 0 |
| 37923359 | 2024 | Integrins regulate hERG1 dynamics by girdin-dependent Gαi3: signaling and modeling in cancer cells. | 0 |
| 36604355 | 2023 | Girdin acts as an oncogene in gastric cancer by regulating AKT/GSK3β/β-catenin signaling. | 0 |
| 37357876 | 2023 | The association between the CCDC88A gene polymorphism at rs1437396 and alcohol use disorder, with or without major depression disorder. | 0 |
| 37478565 | 2023 | An unusual signal transducer GIV/Girdin engages in the roles of adipocyte-derived hormone leptin in liver fibrosis. | 0 |
| 37503752 | 2023 | Girdin regulates both migration and angiogenesis in pancreatic cancer cell lines. | 1 |
| 37532779 | 2023 | hsa-miR-199b-3p suppresses osteosarcoma progression by targeting CCDC88A, inhibiting epithelial-to-mesenchymal transition, and Wnt/beta-catenin signaling pathway. | 0 |
| 37548867 | 2023 | Upregulation of girdin delays endothelial cell apoptosis via promoting engulfment of platelets. | 2 |
| 36604355 | 2023 | Girdin acts as an oncogene in gastric cancer by regulating AKT/GSK3β/β-catenin signaling. | 0 |
| 37357876 | 2023 | The association between the CCDC88A gene polymorphism at rs1437396 and alcohol use disorder, with or without major depression disorder. | 0 |
| 37478565 | 2023 | An unusual signal transducer GIV/Girdin engages in the roles of adipocyte-derived hormone leptin in liver fibrosis. | 0 |
| 37503752 | 2023 | Girdin regulates both migration and angiogenesis in pancreatic cancer cell lines. | 1 |
| 37532779 | 2023 | hsa-miR-199b-3p suppresses osteosarcoma progression by targeting CCDC88A, inhibiting epithelial-to-mesenchymal transition, and Wnt/beta-catenin signaling pathway. | 0 |
| 37548867 | 2023 | Upregulation of girdin delays endothelial cell apoptosis via promoting engulfment of platelets. | 2 |
| 34190023 | 2022 | CCDC88A/GIV promotes HBV replication and progeny secretion via enhancing endosomal trafficking and blocking autophagic degradation. | 8 |
Citation
Dessen P
CCDC88A (coiled-coil domain containing 88A)
Atlas Genet Cytogenet Oncol Haematol. 2008-07-01
Online version: http://atlasgeneticsoncology.org/gene/50215/ccdc88a
