Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 197342
MIM: 610886
HGNC: 27289
Ensembl: ENSG00000197774
Variants:
dbSNP: 197342
ClinVar: 197342
TCGA: ENSG00000197774
COSMIC: EME2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000197774 | ENST00000561903 | H3BV62 |
| ENSG00000197774 | ENST00000564182 | H3BSZ6 |
| ENSG00000197774 | ENST00000568449 | A4GXA9 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35290797 | 2022 | Crystal structure of the human MUS81-EME2 complex. | 3 |
| 35290797 | 2022 | Crystal structure of the human MUS81-EME2 complex. | 3 |
| 26804904 | 2016 | Signaling from Mus81-Eme2-Dependent DNA Damage Elicited by Chk1 Deficiency Modulates Replication Fork Speed and Origin Usage. | 41 |
| 26804904 | 2016 | Signaling from Mus81-Eme2-Dependent DNA Damage Elicited by Chk1 Deficiency Modulates Replication Fork Speed and Origin Usage. | 41 |
| 24371268 | 2014 | Substrate specificity of the MUS81-EME2 structure selective endonuclease. | 35 |
| 24692662 | 2014 | Human MUS81-EME2 can cleave a variety of DNA structures including intact Holliday junction and nicked duplex. | 22 |
| 24813886 | 2014 | MUS81-EME2 promotes replication fork restart. | 68 |
| 24371268 | 2014 | Substrate specificity of the MUS81-EME2 structure selective endonuclease. | 35 |
| 24692662 | 2014 | Human MUS81-EME2 can cleave a variety of DNA structures including intact Holliday junction and nicked duplex. | 22 |
| 24813886 | 2014 | MUS81-EME2 promotes replication fork restart. | 68 |
Citation
Dessen P
EME2 (essential meiotic structure-specific endonuclease subunit 2)
Atlas Genet Cytogenet Oncol Haematol. 2008-07-01
Online version: http://atlasgeneticsoncology.org/gene/50227/eme2
