ESCO2 (establishment of sister chromatid cohesion N-acetyltransferase 2)

2008-07-01  

Identity

HGNC
ESCO2
LOCATION
8p21.1
LOCUSID
157570
ALIAS
2410004I17Rik,EFO2,EFO2p,JHS,RBS,hEFO2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 157570
MIM: 609353
HGNC: 27230
Ensembl: ENSG00000171320

Variants:

dbSNP: 157570
ClinVar: 157570
TCGA: ENSG00000171320
COSMIC: ESCO2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171320ENST00000305188Q56NI9
ENSG00000171320ENST00000397418Q56NI9
ENSG00000171320ENST00000518262H0YB88
ENSG00000171320ENST00000519637E5RFP7
ENSG00000171320ENST00000522378E5RFE4
ENSG00000171320ENST00000523566E5RIE3

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
S PhaseREACTOMER-HSA-69242
Establishment of Sister Chromatid CohesionREACTOMER-HSA-2468052

References

Pubmed IDYearTitleCitations
386053492024ESCO2's oncogenic role in human tumors: a pan-cancer analysis and experimental validation.0
386053492024ESCO2's oncogenic role in human tumors: a pan-cancer analysis and experimental validation.0
361046382023Upregulation of KAT2B and ESCO2 gene expression level in patients with rheumatoid arthritis.2
369120842023Symmetric control of sister chromatid cohesion establishment.0
377159942023Circular RNA METTL15/miR-374a-5p/ESCO2 axis induces colorectal cancer development.0
361046382023Upregulation of KAT2B and ESCO2 gene expression level in patients with rheumatoid arthritis.2
369120842023Symmetric control of sister chromatid cohesion establishment.0
377159942023Circular RNA METTL15/miR-374a-5p/ESCO2 axis induces colorectal cancer development.0
350080042022Effects of ESCO2 or its methylation on the prognosis, clinical characteristics, immune microenvironment, and pathogenesis of low-grade glioma.2
352581732022Long noncoding RNA ZFPM2-AS1 regulates renal cell carcinoma progression via miR-130a-3p/ESCO2.1
350080042022Effects of ESCO2 or its methylation on the prognosis, clinical characteristics, immune microenvironment, and pathogenesis of low-grade glioma.2
352581732022Long noncoding RNA ZFPM2-AS1 regulates renal cell carcinoma progression via miR-130a-3p/ESCO2.1
335736892021ESCO2 promotes lung adenocarcinoma progression by regulating hnRNPA1 acetylation.20
335736892021ESCO2 promotes lung adenocarcinoma progression by regulating hnRNPA1 acetylation.20
319352212020Non-redundant roles in sister chromatid cohesion of the DNA helicase DDX11 and the SMC3 acetyl transferases ESCO1 and ESCO2.13

Citation

Dessen P

ESCO2 (establishment of sister chromatid cohesion N-acetyltransferase 2)

Atlas Genet Cytogenet Oncol Haematol. 2008-07-01

Online version: http://atlasgeneticsoncology.org/gene/50243/css/js/lib/all.min.js