DACH1 (dachshund family transcription factor 1)

2008-07-01  

Identity

HGNC
DACH1
LOCATION
13q21.33
LOCUSID
1602
ALIAS
DACH
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 1602
MIM: 603803
HGNC: 2663
Ensembl: ENSG00000276644

Variants:

dbSNP: 1602
ClinVar: 1602
TCGA: ENSG00000276644
COSMIC: DACH1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000276644ENST00000611519Q9UI36
ENSG00000276644ENST00000613252Q9UI36
ENSG00000276644ENST00000619232Q9UI36
ENSG00000276644ENST00000620444Q9UI36

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
381472892024DACH1 attenuated PA-induced renal tubular injury through TLR4/MyD88/NF-κB and TGF-β/Smad signalling pathway.0
385420742024Dachshund Homolog 1: Unveiling Its Potential Role in Megakaryopoiesis and Bacillus anthracis Lethal Toxin-Induced Thrombocytopenia.0
381472892024DACH1 attenuated PA-induced renal tubular injury through TLR4/MyD88/NF-κB and TGF-β/Smad signalling pathway.0
385420742024Dachshund Homolog 1: Unveiling Its Potential Role in Megakaryopoiesis and Bacillus anthracis Lethal Toxin-Induced Thrombocytopenia.0
365111822023DACH1 inhibits the proliferation and migration of papillary thyroid carcinoma.1
367542762023Dach1 deficiency drives alveolar epithelium apoptosis in pulmonary fibrosis via modulating C-Jun/Bim activity.5
372439702023DACH1 regulates macrophage activation and tumour progression in hypopharyngeal squamous cell carcinoma.2
365111822023DACH1 inhibits the proliferation and migration of papillary thyroid carcinoma.1
367542762023Dach1 deficiency drives alveolar epithelium apoptosis in pulmonary fibrosis via modulating C-Jun/Bim activity.5
372439702023DACH1 regulates macrophage activation and tumour progression in hypopharyngeal squamous cell carcinoma.2
329247842022Mechanistic insight of DACH1 receptor in the development of carcinoma insurgence through MD simulation studies.3
329247842022Mechanistic insight of DACH1 receptor in the development of carcinoma insurgence through MD simulation studies.3
333139422021Upregulation of microRNA‑140‑3p mediates dachshund family transcription factor 1 expression in immunoglobulin A nephropathy through cell cycle‑dependent mechanisms.1
334634632021Role of DACH1 on Proliferation, Invasion, and Apoptosis in Human Lung Adenocarcinoma Cells.4
339985982021Transcriptome-wide association analysis identifies DACH1 as a kidney disease risk gene that contributes to fibrosis.34

Citation

Dessen P

DACH1 (dachshund family transcription factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2008-07-01

Online version: http://atlasgeneticsoncology.org/gene/50251/gene-explorer/cancer-prone-explorer/css/template-nav.css