MORF4L2 (mortality factor 4 like 2)

2008-07-01  

Identity

HGNC
MORF4L2
LOCATION
Xq22.2
LOCUSID
9643
ALIAS
MORFL2,MRGX
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9643
MIM: 300409
HGNC: 16849
Ensembl: ENSG00000123562

Variants:

dbSNP: 9643
ClinVar: 9643
TCGA: ENSG00000123562
COSMIC: MORF4L2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000123562ENST00000360458Q15014
ENSG00000123562ENST00000418819Q5JXX2
ENSG00000123562ENST00000422154Q15014
ENSG00000123562ENST00000422355Q5JXX6
ENSG00000123562ENST00000423833A0A0A0MT59
ENSG00000123562ENST00000433176Q15014
ENSG00000123562ENST00000434230Q5JXX2
ENSG00000123562ENST00000441076Q15014
ENSG00000123562ENST00000442614Q5JXX1
ENSG00000123562ENST00000451301Q15014

Expression (GTEx)

0
100
200
300
400
500
600
700
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Chromatin organizationREACTOMER-HSA-4839726
Chromatin modifying enzymesREACTOMER-HSA-3247509
HATs acetylate histonesREACTOMER-HSA-3214847

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
359008392022miR-3156-5p is downregulated in serum of MEN1 patients and regulates expression of MORF4L2.5
359008392022miR-3156-5p is downregulated in serum of MEN1 patients and regulates expression of MORF4L2.5
330112232020Identification of hub genes in unstable atherosclerotic plaque by conjoint analysis of bioinformatics.5
330112232020Identification of hub genes in unstable atherosclerotic plaque by conjoint analysis of bioinformatics.5
257966272015Enhancement of tumor initiation and expression of KCNMA1, MORF4L2 and ASPM genes in the adenocarcinoma of lung xenograft after vorinostat treatment.10
257966272015Enhancement of tumor initiation and expression of KCNMA1, MORF4L2 and ASPM genes in the adenocarcinoma of lung xenograft after vorinostat treatment.10
185938932008Single-cell transcription site activation predicts chemotherapy response in human colorectal tumors.6
185938932008Single-cell transcription site activation predicts chemotherapy response in human colorectal tumors.6
145062502003MRGX is a novel transcriptional regulator that exhibits activation or repression of the B-myb promoter in a cell type-dependent manner.11
145062502003MRGX is a novel transcriptional regulator that exhibits activation or repression of the B-myb promoter in a cell type-dependent manner.11

Citation

Dessen P

MORF4L2 (mortality factor 4 like 2)

Atlas Genet Cytogenet Oncol Haematol. 2008-07-01

Online version: http://atlasgeneticsoncology.org/gene/50257/teaching-explorer/js/teaching-explorer/