Identity
HGNC
LOCATION
5q33.1
LOCUSID
ALIAS
Dct1,LYAAT1,PAT1,TRAMD3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 206358
MIM: 606561
HGNC: 18761
Ensembl: ENSG00000123643
Variants:
dbSNP: 206358
ClinVar: 206358
TCGA: ENSG00000123643
COSMIC: SLC36A1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30253187 | 2019 | The amino acid transporter PAT1 regulates mTORC1 in a nutrient-sensitive manner that requires its transport activity. | 3 |
| 31555743 | 2019 | SLC36A1-mTORC1 signaling drives acquired resistance to CDK4/6 inhibitors. | 20 |
| 30253187 | 2019 | The amino acid transporter PAT1 regulates mTORC1 in a nutrient-sensitive manner that requires its transport activity. | 3 |
| 31555743 | 2019 | SLC36A1-mTORC1 signaling drives acquired resistance to CDK4/6 inhibitors. | 20 |
| 28117901 | 2017 | Glycosylation affects the stability and subcellular distribution of human PAT1 protein. | 3 |
| 28670736 | 2017 | Amino acids suppress the expression of PAT1 on lysosomes via inducing the cleavage of a targeting signal. | 0 |
| 28117901 | 2017 | Glycosylation affects the stability and subcellular distribution of human PAT1 protein. | 3 |
| 28670736 | 2017 | Amino acids suppress the expression of PAT1 on lysosomes via inducing the cleavage of a targeting signal. | 0 |
| 23488788 | 2013 | Transport of the areca nut alkaloid arecaidine by the human proton-coupled amino acid transporter 1 (hPAT1). | 2 |
| 23962042 | 2013 | Sertraline inhibits the transport of PAT1 substrates in vivo and in vitro. | 5 |
| 23488788 | 2013 | Transport of the areca nut alkaloid arecaidine by the human proton-coupled amino acid transporter 1 (hPAT1). | 2 |
| 23962042 | 2013 | Sertraline inhibits the transport of PAT1 substrates in vivo and in vitro. | 5 |
| 22574197 | 2012 | Proton-assisted amino acid transporter PAT1 complexes with Rag GTPases and activates TORC1 on late endosomal and lysosomal membranes. | 74 |
| 22853447 | 2012 | Intestinal drug transport via the proton-coupled amino acid transporter PAT1 (SLC36A1) is inhibited by Gly-X(aa) dipeptides. | 4 |
| 22975709 | 2012 | Estradiol inhibits the activity of proton-coupled amino acid transporter PAT1 expressed in Xenopus oocytes. | 1 |
Citation
Dessen P
SLC36A1 (solute carrier family 36 member 1)
Atlas Genet Cytogenet Oncol Haematol. 2008-07-01
Online version: http://atlasgeneticsoncology.org/gene/50264/slc36a1
