Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55366
MIM: 606666
HGNC: 13299
Ensembl: ENSG00000205213
Variants:
dbSNP: 55366
ClinVar: 55366
TCGA: ENSG00000205213
COSMIC: LGR4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000205213 | ENST00000379214 | Q9BXB1 |
| ENSG00000205213 | ENST00000389858 | Q9BXB1 |
| ENSG00000205213 | ENST00000480977 | E9PK51 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37437654 | 2024 | Rspo2-LGR4 exacerbates hepatocellular carcinoma progression via activation of Wnt/β-catenin signaling pathway. | 0 |
| 37437654 | 2024 | Rspo2-LGR4 exacerbates hepatocellular carcinoma progression via activation of Wnt/β-catenin signaling pathway. | 0 |
| 36538378 | 2023 | Loss of LGR4/GPR48 causes severe neonatal salt wasting due to disrupted WNT signaling altering adrenal zonation. | 3 |
| 36791020 | 2023 | LGR4: A New Receptor Member in Endocrine and Metabolic Diseases. | 3 |
| 37473901 | 2023 | LGR4 promotes tumorigenesis by activating TGF-β1/Smad signaling pathway in multiple myeloma. | 0 |
| 37986325 | 2023 | Identification of LGR4 as a prognostic biomarker in KRAS-mutant lung adenocarcinoma: Evidence from integrated bioinformatics analysis. | 0 |
| 36538378 | 2023 | Loss of LGR4/GPR48 causes severe neonatal salt wasting due to disrupted WNT signaling altering adrenal zonation. | 3 |
| 36791020 | 2023 | LGR4: A New Receptor Member in Endocrine and Metabolic Diseases. | 3 |
| 37473901 | 2023 | LGR4 promotes tumorigenesis by activating TGF-β1/Smad signaling pathway in multiple myeloma. | 0 |
| 37986325 | 2023 | Identification of LGR4 as a prognostic biomarker in KRAS-mutant lung adenocarcinoma: Evidence from integrated bioinformatics analysis. | 0 |
| 34847079 | 2022 | RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formation and bone metastasis. | 19 |
| 36008975 | 2022 | Bioinformatics Analysis of LGR4 in Colon Adenocarcinoma as Potential Diagnostic Biomarker, Therapeutic Target and Promoting Immune Cell Infiltration. | 5 |
| 34847079 | 2022 | RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formation and bone metastasis. | 19 |
| 36008975 | 2022 | Bioinformatics Analysis of LGR4 in Colon Adenocarcinoma as Potential Diagnostic Biomarker, Therapeutic Target and Promoting Immune Cell Infiltration. | 5 |
| 33171177 | 2021 | Ablation of LGR4 signaling enhances radiation sensitivity of prostate cancer cells. | 2 |
Citation
Dessen P
LGR4 (leucine rich repeat containing G protein-coupled receptor 4)
Atlas Genet Cytogenet Oncol Haematol. 2008-07-01
Online version: http://atlasgeneticsoncology.org/gene/50275/lgr4
