Identity
HGNC
LOCATION
9p13.3
LOCUSID
ALIAS
AMCD1,DA1,DA2B,DA2B4,HEL-S-273,NEM4,TMSB
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7169
MIM: 190990
HGNC: 12011
Ensembl: ENSG00000198467
Variants:
dbSNP: 7169
ClinVar: 7169
TCGA: ENSG00000198467
COSMIC: TPM2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38219297 | 2024 | Variants in tropomyosins TPM2 and TPM3 causing muscle hypertonia. | 0 |
| 38219297 | 2024 | Variants in tropomyosins TPM2 and TPM3 causing muscle hypertonia. | 0 |
| 33919826 | 2021 | Mutations Q93H and E97K in TPM2 Disrupt Ca-Dependent Regulation of Actin Filaments. | 5 |
| 33919826 | 2021 | Mutations Q93H and E97K in TPM2 Disrupt Ca-Dependent Regulation of Actin Filaments. | 5 |
| 32092148 | 2020 | A recurrent pathogenic variant in TPM2 reveals further phenotypic and genetic heterogeneity in multiple pterygium syndrome-related disorders. | 3 |
| 32957762 | 2020 | [Expression of tropomyosin 2 in aortic dissection tissue]. | 2 |
| 33066566 | 2020 | Looking for Targets to Restore the Contractile Function in Congenital Myopathy Caused by Gln(147)Pro Tropomyosin. | 3 |
| 32092148 | 2020 | A recurrent pathogenic variant in TPM2 reveals further phenotypic and genetic heterogeneity in multiple pterygium syndrome-related disorders. | 3 |
| 32957762 | 2020 | [Expression of tropomyosin 2 in aortic dissection tissue]. | 2 |
| 33066566 | 2020 | Looking for Targets to Restore the Contractile Function in Congenital Myopathy Caused by Gln(147)Pro Tropomyosin. | 3 |
| 30535593 | 2019 | Tropomyosin Tpm 2.1 loss induces glioblastoma spreading in soft brain-like environments. | 6 |
| 30545627 | 2019 | Structural and functional properties of αβ-heterodimers of tropomyosin with myopathic mutations Q147P and K49del in the β-chain. | 4 |
| 31487691 | 2019 | TPM2 as a potential predictive biomarker for atherosclerosis. | 36 |
| 30535593 | 2019 | Tropomyosin Tpm 2.1 loss induces glioblastoma spreading in soft brain-like environments. | 6 |
| 30545627 | 2019 | Structural and functional properties of αβ-heterodimers of tropomyosin with myopathic mutations Q147P and K49del in the β-chain. | 4 |
Citation
Dessen P
TPM2 (tropomyosin 2)
Atlas Genet Cytogenet Oncol Haematol. 2008-08-01
Online version: http://atlasgeneticsoncology.org/gene/50293/tpm2
