FSCN2 (fascin actin-bundling protein 2, retinal)

2008-08-01  

Identity

HGNC
FSCN2
LOCATION
17q25.3
LOCUSID
25794
ALIAS
RFSN,RP30

Other Information

Locus ID:

NCBI: 25794
MIM: 607643
HGNC: 3960
Ensembl: ENSG00000186765

Variants:

dbSNP: 25794
ClinVar: 25794
TCGA: ENSG00000186765
COSMIC: FSCN2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000186765ENST00000334850O14926
ENSG00000186765ENST00000417245O14926

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
344771722021Fascin as a useful marker for cancer-associated fibroblasts in invasive lung adenocarcinoma.2
344771722021Fascin as a useful marker for cancer-associated fibroblasts in invasive lung adenocarcinoma.2
299700862018Fascin induces melanoma tumorigenesis and stemness through regulating the Hippo pathway.13
299700862018Fascin induces melanoma tumorigenesis and stemness through regulating the Hippo pathway.13
282722242017High expression of SALL4 and fascin, and loss of E-cadherin expression in undifferentiated/dedifferentiated carcinomas of the endometrium: An immunohistochemical and clinicopathologic study.6
282722242017High expression of SALL4 and fascin, and loss of E-cadherin expression in undifferentiated/dedifferentiated carcinomas of the endometrium: An immunohistochemical and clinicopathologic study.6
263632192015Regulation of the tumor marker Fascin by the viral oncoprotein Tax of human T-cell leukemia virus type 1 (HTLV-1) depends on promoter activation and on a promoter-independent mechanism.10
263632192015Regulation of the tumor marker Fascin by the viral oncoprotein Tax of human T-cell leukemia virus type 1 (HTLV-1) depends on promoter activation and on a promoter-independent mechanism.10
244144192014Stratifying fascin and cortactin function in invadopodium formation using inhibitory nanobodies and targeted subcellular delocalization.33
244144192014Stratifying fascin and cortactin function in invadopodium formation using inhibitory nanobodies and targeted subcellular delocalization.33
240705742013Serological investigation of the clinical significance of fascin in non-small-cell lung cancer.12
240705742013Serological investigation of the clinical significance of fascin in non-small-cell lung cancer.12
219755522011The filopodium: a stable structure with highly regulated repetitive cycles of elongation and persistence depending on the actin cross-linker fascin.14
219755522011The filopodium: a stable structure with highly regulated repetitive cycles of elongation and persistence depending on the actin cross-linker fascin.14
204108082010Fascin expression predicts survival after potentially curative resection of node-positive colon cancer.15

Citation

Dessen P

FSCN2 (fascin actin-bundling protein 2, retinal)

Atlas Genet Cytogenet Oncol Haematol. 2008-08-01

Online version: http://atlasgeneticsoncology.org/gene/50295