Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 11255
MIM: 604525
HGNC: 5184
Ensembl: ENSG00000101180
Variants:
dbSNP: 11255
ClinVar: 11255
TCGA: ENSG00000101180
COSMIC: HRH3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000101180 | ENST00000317393 | A0A0A0MR48 |
| ENSG00000101180 | ENST00000340177 | Q9Y5N1 |
| ENSG00000101180 | ENST00000611492 | A0A087WZD3 |
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447216 | Schizophrenia | Disease | ClinicalAnnotation | associated | PD | 21652606 | |
| PA451257 | risperidone | Chemical | ClinicalAnnotation | associated | PD | 21652606 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37752220 | 2023 | Recovery of the histamine H(3) receptor activity lost in yeast cells through error-prone PCR and in vivo selection. | 0 |
| 37752220 | 2023 | Recovery of the histamine H(3) receptor activity lost in yeast cells through error-prone PCR and in vivo selection. | 0 |
| 36091066 | 2022 | Unraveling the venom chemistry with evidence for histamine as key regulator in the envenomation by caterpillar Automeris zaruma. | 4 |
| 36091066 | 2022 | Unraveling the venom chemistry with evidence for histamine as key regulator in the envenomation by caterpillar Automeris zaruma. | 4 |
| 30801695 | 2020 | Histamine, histamine H(3) receptor, and alcohol use disorder. | 5 |
| 33063610 | 2020 | Histamine H(3) receptor gene variants associated with drug abuse in patients with cocaine use disorder. | 0 |
| 30801695 | 2020 | Histamine, histamine H(3) receptor, and alcohol use disorder. | 5 |
| 33063610 | 2020 | Histamine H(3) receptor gene variants associated with drug abuse in patients with cocaine use disorder. | 0 |
| 31002350 | 2019 | Upregulated histamine receptor H3 promotes tumor growth and metastasis in hepatocellular carcinoma. | 10 |
| 31002350 | 2019 | Upregulated histamine receptor H3 promotes tumor growth and metastasis in hepatocellular carcinoma. | 10 |
| 29557708 | 2018 | Differential expression and signaling of the human histamine H(3) receptor isoforms of 445 and 365 amino acids expressed in human neuroblastoma SH-SY5Y cells. | 0 |
| 29557708 | 2018 | Differential expression and signaling of the human histamine H(3) receptor isoforms of 445 and 365 amino acids expressed in human neuroblastoma SH-SY5Y cells. | 0 |
| 28126588 | 2017 | The naturally occurring mutation Y197C does not affect the expression or signaling of the human histamine H(3) receptor. | 0 |
| 29253893 | 2017 | Histamine Receptor 3 negatively regulates oligodendrocyte differentiation and remyelination. | 23 |
| 28126588 | 2017 | The naturally occurring mutation Y197C does not affect the expression or signaling of the human histamine H(3) receptor. | 0 |
Citation
Dessen P
HRH3 (histamine receptor H3)
Atlas Genet Cytogenet Oncol Haematol. 2008-08-01
Online version: http://atlasgeneticsoncology.org/gene/50307/hrh3
