TMBIM4 (transmembrane BAX inhibitor motif containing 4)

2008-08-01  

Identity

HGNC
TMBIM4
LOCATION
12q14.3
LOCUSID
51643
ALIAS
CGI-119,GAAP,LFG4,S1R,ZPRO
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51643
MIM: 616874
HGNC: 24257
Ensembl: ENSG00000155957

Variants:

dbSNP: 51643
ClinVar: 51643
TCGA: ENSG00000155957
COSMIC: TMBIM4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000155957ENST00000286424G3XAA5
ENSG00000155957ENST00000358230Q9HC24
ENSG00000155957ENST00000398033E7EWY5
ENSG00000155957ENST00000534930F5GXT9
ENSG00000155957ENST00000535812F5GXT9
ENSG00000155957ENST00000542724G3V1M2
ENSG00000155957ENST00000544599G3V1R8
ENSG00000155957ENST00000545407F5GXT9
ENSG00000155957ENST00000545504F5H1S4
ENSG00000155957ENST00000556010L7MUG5
ENSG00000155957ENST00000613669A0A087WXH1
ENSG00000155957ENST00000633367Q7Z782

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
316939772020Stimulation of cell invasion by the Golgi Ion Channel GAAP/TMBIM4 via an H(2)O(2)-Dependent Mechanism.8
316939772020Stimulation of cell invasion by the Golgi Ion Channel GAAP/TMBIM4 via an H(2)O(2)-Dependent Mechanism.8
284690072017Golgi anti-apoptotic protein: a tale of camels, calcium, channels and cancer.19
284690072017Golgi anti-apoptotic protein: a tale of camels, calcium, channels and cancer.19
257649782015The transmembrane Bax inhibitor motif (TMBIM) containing protein family: Tissue expression, intracellular localization and effects on the ER CA²⁺-filling state.40
257649782015The transmembrane Bax inhibitor motif (TMBIM) containing protein family: Tissue expression, intracellular localization and effects on the ER CA²⁺-filling state.40
230009032013Host cell Golgi anti-apoptotic protein (GAAP) and growth of Chlamydia pneumoniae.1
235089502013Human and viral Golgi anti-apoptotic proteins (GAAPs) oligomerize via different mechanisms and monomeric GAAP inhibits apoptosis and modulates calcium.15
239401162013hGAAP promotes cell adhesion and migration via the stimulation of store-operated Ca2+ entry and calpain 2.29
230009032013Host cell Golgi anti-apoptotic protein (GAAP) and growth of Chlamydia pneumoniae.1
235089502013Human and viral Golgi anti-apoptotic proteins (GAAPs) oligomerize via different mechanisms and monomeric GAAP inhibits apoptosis and modulates calcium.15
239401162013hGAAP promotes cell adhesion and migration via the stimulation of store-operated Ca2+ entry and calpain 2.29
224184392012Six-transmembrane topology for Golgi anti-apoptotic protein (GAAP) and Bax inhibitor 1 (BI-1) provides model for the transmembrane Bax inhibitor-containing motif (TMBIM) family.31
224184392012Six-transmembrane topology for Golgi anti-apoptotic protein (GAAP) and Bax inhibitor 1 (BI-1) provides model for the transmembrane Bax inhibitor-containing motif (TMBIM) family.31
195534692009Human Golgi antiapoptotic protein modulates intracellular calcium fluxes.30

Citation

Dessen P

TMBIM4 (transmembrane BAX inhibitor motif containing 4)

Atlas Genet Cytogenet Oncol Haematol. 2008-08-01

Online version: http://atlasgeneticsoncology.org/gene/50313/css/lib/gene-fusions/?id=50313