SP4 (Sp4 transcription factor)

2008-09-01  

Identity

HGNC
SP4
LOCATION
7p15.3
LOCUSID
6671
ALIAS
HF1B,SPR-1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6671
MIM: 600540
HGNC: 11209
Ensembl: ENSG00000105866

Variants:

dbSNP: 6671
ClinVar: 6671
TCGA: ENSG00000105866
COSMIC: SP4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105866ENST00000222584Q02446
ENSG00000105866ENST00000432066C9JUS7
ENSG00000105866ENST00000448246F8WB93
ENSG00000105866ENST00000649633A0A3B3IRW4

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
377681802024SP4 Facilitates Esophageal Squamous Cell Carcinoma Progression by Activating PHF14 Transcription and Wnt/Β-Catenin Signaling.0
377681802024SP4 Facilitates Esophageal Squamous Cell Carcinoma Progression by Activating PHF14 Transcription and Wnt/Β-Catenin Signaling.0
347505022022Over-representation of potential SP4 target genes within schizophrenia-risk genes.4
363460672022The genetic polymorphisms in the SP4 gene and the risk of gastric cancer.2
363720092022Common and rare variants within SP4 exert distinct molecular mechanisms contributing to the risk of schizophrenia.0
363831362022Sp4 Regulates PTTG1IP Gene Transcription and Expression.0
371142562022The FOXP4-AS1/miR-3130-3p/SP4 feedback loop is associated with prostate cancer.0
347505022022Over-representation of potential SP4 target genes within schizophrenia-risk genes.4
363460672022The genetic polymorphisms in the SP4 gene and the risk of gastric cancer.2
363720092022Common and rare variants within SP4 exert distinct molecular mechanisms contributing to the risk of schizophrenia.0
363831362022Sp4 Regulates PTTG1IP Gene Transcription and Expression.0
371142562022The FOXP4-AS1/miR-3130-3p/SP4 feedback loop is associated with prostate cancer.0
280813712017GWAS Identifies New Loci for Painful Temporomandibular Disorder: Hispanic Community Health Study/Study of Latinos.16
280813712017GWAS Identifies New Loci for Painful Temporomandibular Disorder: Hispanic Community Health Study/Study of Latinos.16
264505792016Role played by the SP4 gene in schizophrenia and major depressive disorder in the Han Chinese population.0

Citation

Dessen P

SP4 (Sp4 transcription factor)

Atlas Genet Cytogenet Oncol Haematol. 2008-09-01

Online version: http://atlasgeneticsoncology.org/gene/50320