INA (internexin neuronal intermediate filament protein alpha)

2008-09-01  

Identity

HGNC
INA
LOCATION
10q24.33
LOCUSID
9118
ALIAS
NEF5,NF-66,TXBP-1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9118
MIM: 605338
HGNC: 6057
Ensembl: ENSG00000148798

Variants:

dbSNP: 9118
ClinVar: 9118
TCGA: ENSG00000148798
COSMIC: INA

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000148798ENST00000369849Q16352

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
330512522020Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer.13
330512522020Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer.13
293390732018The human GCOM1 complex gene interacts with the NMDA receptor and internexin-alpha.4
299408922018Loss of expression and prognosis value of alpha-internexin in gastroenteropancreatic neuroendocrine neoplasm.4
293390732018The human GCOM1 complex gene interacts with the NMDA receptor and internexin-alpha.4
299408922018Loss of expression and prognosis value of alpha-internexin in gastroenteropancreatic neuroendocrine neoplasm.4
285268802017Prognostic relevance of UCH-L1 and α-internexin in pancreatic neuroendocrine tumors.9
285268802017Prognostic relevance of UCH-L1 and α-internexin in pancreatic neuroendocrine tumors.9
252364352015Expression pattern of neuronal intermediate filament α-internexin in anterior pituitary gland and related tumors.5
262335222015Coexpression of cyclin D1 and alpha-internexin in oligodendroglial tumors.4
252364352015Expression pattern of neuronal intermediate filament α-internexin in anterior pituitary gland and related tumors.5
262335222015Coexpression of cyclin D1 and alpha-internexin in oligodendroglial tumors.4
241978632014Alpha-internexin and altered CIC expression as a supportive diagnostic marker for oligodendroglial tumors with the 1p/19q co-deletion.2
244831522014α-Internexin: a novel biomarker for pancreatic neuroendocrine tumor aggressiveness.10
241978632014Alpha-internexin and altered CIC expression as a supportive diagnostic marker for oligodendroglial tumors with the 1p/19q co-deletion.2

Citation

Dessen P

INA (internexin neuronal intermediate filament protein alpha)

Atlas Genet Cytogenet Oncol Haematol. 2008-09-01

Online version: http://atlasgeneticsoncology.org/gene/50337