Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 27121
MIM: 605417
HGNC: 2894
Ensembl: ENSG00000104371
Variants:
dbSNP: 27121
ClinVar: 27121
TCGA: ENSG00000104371
COSMIC: DKK4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000104371 | ENST00000220812 | Q9UBT3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32713860 | 2020 | Sensitization of hepatocellular carcinoma cells towards doxorubicin and sorafenib is facilitated by glucosedependent alterations in reactive oxygen species, P-glycoprotein and DKK4. | 10 |
| 32713860 | 2020 | Sensitization of hepatocellular carcinoma cells towards doxorubicin and sorafenib is facilitated by glucosedependent alterations in reactive oxygen species, P-glycoprotein and DKK4. | 10 |
| 31202458 | 2019 | DLX3 regulates osteogenic differentiation of bone marrow mesenchymal stem cells via Wnt/β-catenin pathway mediated histone methylation of DKK4. | 8 |
| 31202458 | 2019 | DLX3 regulates osteogenic differentiation of bone marrow mesenchymal stem cells via Wnt/β-catenin pathway mediated histone methylation of DKK4. | 8 |
| 29925589 | 2018 | Structural and functional analysis of Dickkopf 4 (Dkk4): New insights into Dkk evolution and regulation of Wnt signaling by Dkk and Kremen proteins. | 14 |
| 29925589 | 2018 | Structural and functional analysis of Dickkopf 4 (Dkk4): New insights into Dkk evolution and regulation of Wnt signaling by Dkk and Kremen proteins. | 14 |
| 28005267 | 2017 | Human gingiva transcriptome during wound healing. | 14 |
| 28450117 | 2017 | TCF7L1 recruits CtBP and HDAC1 to repress DICKKOPF4 gene expression in human colorectal cancer cells. | 14 |
| 28666421 | 2017 | Dickkopf-4 is frequently overexpressed in epithelial ovarian carcinoma and promotes tumor invasion. | 10 |
| 28981599 | 2017 | DKK4-knockdown enhances chemosensitivity of A549/DTX cells to docetaxel. | 6 |
| 28005267 | 2017 | Human gingiva transcriptome during wound healing. | 14 |
| 28450117 | 2017 | TCF7L1 recruits CtBP and HDAC1 to repress DICKKOPF4 gene expression in human colorectal cancer cells. | 14 |
| 28666421 | 2017 | Dickkopf-4 is frequently overexpressed in epithelial ovarian carcinoma and promotes tumor invasion. | 10 |
| 28981599 | 2017 | DKK4-knockdown enhances chemosensitivity of A549/DTX cells to docetaxel. | 6 |
| 26880586 | 2016 | Transcriptomic changes associated with DKK4 overexpression in pancreatic cancer cells detected by RNA-Seq. | 14 |
Citation
Dessen P
DKK4 (dickkopf WNT signaling pathway inhibitor 4)
Atlas Genet Cytogenet Oncol Haematol. 2008-09-01
Online version: http://atlasgeneticsoncology.org/gene/50347/dkk4
