RHOD (ras homolog family member D)

2008-09-01  

Identity

HGNC
RHOD
LOCATION
11q13.2
LOCUSID
29984
ALIAS
ARHD,RHOHP1,RHOM,Rho
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 29984
MIM: 605781
HGNC: 670
Ensembl: ENSG00000173156

Variants:

dbSNP: 29984
ClinVar: 29984
TCGA: ENSG00000173156
COSMIC: RHOD

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173156ENST00000308831O00212
ENSG00000173156ENST00000532559E9PIG5

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Axon guidanceKEGGko04360
Axon guidanceKEGGhsa04360
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
Rho GTPase cycleREACTOMER-HSA-194840
RHO GTPase EffectorsREACTOMER-HSA-195258
RHO GTPases Activate ForminsREACTOMER-HSA-5663220

References

Pubmed IDYearTitleCitations
350871702022Rho GTPase gene expression and breast cancer risk: a Mendelian randomization analysis.2
350871702022Rho GTPase gene expression and breast cancer risk: a Mendelian randomization analysis.2
338723152021The actin nucleation factors JMY and WHAMM enable a rapid Arp2/3 complex-mediated intrinsic pathway of apoptosis.9
338723152021The actin nucleation factors JMY and WHAMM enable a rapid Arp2/3 complex-mediated intrinsic pathway of apoptosis.9
297766642018RhoD localization and function is dependent on its GTP/GDP-bound state and unique N-terminal motif.2
297766642018RhoD localization and function is dependent on its GTP/GDP-bound state and unique N-terminal motif.2
281967282017The atypical Rho GTPase RhoD is a regulator of actin cytoskeleton dynamics and directed cell migration.14
284861332017RhoD Inhibits RhoC-ROCK-Dependent Cell Contraction via PAK6.17
281967282017The atypical Rho GTPase RhoD is a regulator of actin cytoskeleton dynamics and directed cell migration.14
284861332017RhoD Inhibits RhoC-ROCK-Dependent Cell Contraction via PAK6.17
257467242015RhoD is a Golgi component with a role in anterograde protein transport from the ER to the plasma membrane.12
257467242015RhoD is a Golgi component with a role in anterograde protein transport from the ER to the plasma membrane.12
247063582014Paxillin mediates stretch-induced Rho signaling and endothelial permeability via assembly of paxillin-p42/44MAPK-GEF-H1 complex.21
247176052014[Role of the Rho-kinase pathway in pulmonary arterial hypertension].2
247063582014Paxillin mediates stretch-induced Rho signaling and endothelial permeability via assembly of paxillin-p42/44MAPK-GEF-H1 complex.21

Citation

Dessen P

RHOD (ras homolog family member D)

Atlas Genet Cytogenet Oncol Haematol. 2008-09-01

Online version: http://atlasgeneticsoncology.org/gene/50349