Identity
HGNC
LOCATION
17q21.32
LOCUSID
ALIAS
B4GALT,GALGT2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 124872
MIM: 111730
HGNC: 24136
Ensembl: ENSG00000167080
Variants:
dbSNP: 124872
ClinVar: 124872
TCGA: ENSG00000167080
COSMIC: B4GALNT2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000167080 | ENST00000300404 | Q8NHY0 |
| ENSG00000167080 | ENST00000393354 | Q8NHY0 |
| ENSG00000167080 | ENST00000504681 | Q8NHY0 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Metabolism of proteins | REACTOME | R-HSA-392499 |
| Post-translational protein modification | REACTOME | R-HSA-597592 |
| Asparagine N-linked glycosylation | REACTOME | R-HSA-446203 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36835549 | 2023 | N-Glycan on the Non-Consensus N-X-C Glycosylation Site Impacts Activity, Stability, and Localization of the Sd(a) Synthase B4GALNT2. | 0 |
| 36835549 | 2023 | N-Glycan on the Non-Consensus N-X-C Glycosylation Site Impacts Activity, Stability, and Localization of the Sd(a) Synthase B4GALNT2. | 0 |
| 35409292 | 2022 | Glycoproteomic and Phenotypic Elucidation of B4GALNT2 Expression Variants in the SID Histo-Blood Group System. | 1 |
| 35409292 | 2022 | Glycoproteomic and Phenotypic Elucidation of B4GALNT2 Expression Variants in the SID Histo-Blood Group System. | 1 |
| 33662872 | 2021 | The role of the blood group-related glycosyltransferases FUT2 and B4GALNT2 in susceptibility to infectious disease. | 12 |
| 33770101 | 2021 | Short-term treatment of golden retriever muscular dystrophy (GRMD) dogs with rAAVrh74.MHCK7.GALGT2 induces muscle glycosylation and utrophin expression but has no significant effect on muscle strength. | 5 |
| 33919332 | 2021 | Glycosyltransferase B4GALNT2 as a Predictor of Good Prognosis in Colon Cancer: Lessons from Databases. | 10 |
| 34397142 | 2021 | B4GALNT2 Controls Sd(a) and SLe(x) Antigen Biosynthesis in Healthy and Cancer Human Colon. | 0 |
| 34500083 | 2021 | Analysis of the proximal promoter of the human colon-specific B4GALNT2 (Sd(a) synthase) gene: B4GALNT2 is transcriptionally regulated by ETS1. | 3 |
| 33662872 | 2021 | The role of the blood group-related glycosyltransferases FUT2 and B4GALNT2 in susceptibility to infectious disease. | 12 |
| 33770101 | 2021 | Short-term treatment of golden retriever muscular dystrophy (GRMD) dogs with rAAVrh74.MHCK7.GALGT2 induces muscle glycosylation and utrophin expression but has no significant effect on muscle strength. | 5 |
| 33919332 | 2021 | Glycosyltransferase B4GALNT2 as a Predictor of Good Prognosis in Colon Cancer: Lessons from Databases. | 10 |
| 34397142 | 2021 | B4GALNT2 Controls Sd(a) and SLe(x) Antigen Biosynthesis in Healthy and Cancer Human Colon. | 0 |
| 34500083 | 2021 | Analysis of the proximal promoter of the human colon-specific B4GALNT2 (Sd(a) synthase) gene: B4GALNT2 is transcriptionally regulated by ETS1. | 3 |
| 32290493 | 2020 | High Expression of the Sd(a) Synthase B4GALNT2 Associates with Good Prognosis and Attenuates Stemness in Colon Cancer. | 10 |
Citation
Dessen P
B4GALNT2 (beta-1,4-N-acetyl-galactosaminyltransferase 2)
Atlas Genet Cytogenet Oncol Haematol. 2008-09-01
Online version: http://atlasgeneticsoncology.org/gene/50356/b4galnt2
