FSHB (follicle stimulating hormone subunit beta)

2008-10-01  

Identity

HGNC
FSHB
LOCATION
11p14.1
LOCUSID
2488
ALIAS
HH24

Other Information

Locus ID:

NCBI: 2488
MIM: 136530
HGNC: 3964
Ensembl: ENSG00000131808

Variants:

dbSNP: 2488
ClinVar: 2488
TCGA: ENSG00000131808
COSMIC: FSHB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000131808ENST00000254122P01225
ENSG00000131808ENST00000254122A0A0F7RQE8
ENSG00000131808ENST00000417547P01225
ENSG00000131808ENST00000417547A0A0F7RQE8
ENSG00000131808ENST00000533718P01225
ENSG00000131808ENST00000533718A0A0F7RQE8

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Neuroactive ligand-receptor interactionKEGGko04080
GnRH signaling pathwayKEGGko04912
Neuroactive ligand-receptor interactionKEGGhsa04080
GnRH signaling pathwayKEGGhsa04912
Ovarian steroidogenesisKEGGhsa04913
Ovarian steroidogenesisKEGGko04913
cAMP signaling pathwayKEGGhsa04024
cAMP signaling pathwayKEGGko04024
Metabolism of proteinsREACTOMER-HSA-392499
Peptide hormone metabolismREACTOMER-HSA-2980736
Peptide hormone biosynthesisREACTOMER-HSA-209952
Glycoprotein hormonesREACTOMER-HSA-209822
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
Hormone ligand-binding receptorsREACTOMER-HSA-375281
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (s) signalling eventsREACTOMER-HSA-418555

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
pituitary gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
369081592023Spontaneous alterations in semen parameters are associated with age, accessory gland function and the FSHB c.-211G>T variant.0
379096522023Implication of FSHB rs10835638 variant in endometriosis in Brazilian women.0
369081592023Spontaneous alterations in semen parameters are associated with age, accessory gland function and the FSHB c.-211G>T variant.0
379096522023Implication of FSHB rs10835638 variant in endometriosis in Brazilian women.0
349872262022A speech planning network for interactive language use.20
349872262022A speech planning network for interactive language use.20
329945682021Role of FSH and FSH receptor on HUVECs migration.2
330095492021FSHB  Transcription is Regulated by a Novel 5' Distal Enhancer With a Fertility-Associated Single Nucleotide Polymorphism.13
332365192021FSHB and FSHR gene variants exert mild modulatory effect on reproductive hormone levels and testis size but not on semen quality: A study of 2020 men from the general Danish population.0
346591332021Effects of FSHR and FSHB Variants on Hormonal Profile and Reproductive Outcomes of Infertile Women With Endometriosis.12
349925802021FSHB Genotype Identified as a Relevant Diagnostic Parameter Revealed by Cluster Analysis of Men With Idiopathic Infertility.3
329945682021Role of FSH and FSH receptor on HUVECs migration.2
330095492021FSHB  Transcription is Regulated by a Novel 5' Distal Enhancer With a Fertility-Associated Single Nucleotide Polymorphism.13
332365192021FSHB and FSHR gene variants exert mild modulatory effect on reproductive hormone levels and testis size but not on semen quality: A study of 2020 men from the general Danish population.0
346591332021Effects of FSHR and FSHB Variants on Hormonal Profile and Reproductive Outcomes of Infertile Women With Endometriosis.12

Citation

Dessen P

FSHB (follicle stimulating hormone subunit beta)

Atlas Genet Cytogenet Oncol Haematol. 2008-10-01

Online version: http://atlasgeneticsoncology.org/gene/50404/js/cancer-prone-explorer/