LBP (lipopolysaccharide binding protein)

2008-10-01  

Identity

HGNC
LOCATION
20q11.23
LOCUSID
ALIAS
BPIFD2

Other Information

Locus ID:

NCBI: 3929
MIM: 151990
HGNC: 6517
Ensembl: ENSG00000129988

Variants:

dbSNP: 3929
ClinVar: 3929
TCGA: ENSG00000129988
COSMIC: LBP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000129988ENST00000217407P18428

Expression (GTEx)

0
100
200
300
400
500
600
700
800

Pathways

PathwaySourceExternal ID
Toll-like receptor signaling pathwayKEGGko04620
Toll-like receptor signaling pathwayKEGGhsa04620
TuberculosisKEGGko05152
TuberculosisKEGGhsa05152
Salmonella infectionKEGGko05132
Salmonella infectionKEGGhsa05132
NF-kappa B signaling pathwayKEGGhsa04064
NF-kappa B signaling pathwayKEGGko04064
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Toll-Like Receptors CascadesREACTOMER-HSA-168898
Toll Like Receptor 4 (TLR4) CascadeREACTOMER-HSA-166016
Transfer of LPS from LBP carrier to CD14REACTOMER-HSA-166020
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Signaling by InterleukinsREACTOMER-HSA-449147
Regulation of TLR by endogenous ligandREACTOMER-HSA-5686938
Interleukin-4 and 13 signalingREACTOMER-HSA-6785807

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
386150602024Lipopolysaccharide binding protein resists hepatic oxidative stress by regulating lipid droplet homeostasis.0
386150602024Lipopolysaccharide binding protein resists hepatic oxidative stress by regulating lipid droplet homeostasis.0
346533032023Lipopolysaccharide-binding protein as a biomarker in oral and maxillofacial tumors.3
374801142023Lipopolysaccharide-binding protein and future Parkinson's disease risk: a European prospective cohort.3
377893852023Gastric cancer-derived LBP promotes liver metastasis by driving intrahepatic fibrotic pre-metastatic niche formation.3
346533032023Lipopolysaccharide-binding protein as a biomarker in oral and maxillofacial tumors.3
374801142023Lipopolysaccharide-binding protein and future Parkinson's disease risk: a European prospective cohort.3
377893852023Gastric cancer-derived LBP promotes liver metastasis by driving intrahepatic fibrotic pre-metastatic niche formation.3
352945312022Identification of CD14 and lipopolysaccharide-binding protein as novel biomarkers for sarcoidosis using proteomics of serum extracellular vesicles.7
353321762022SWATH-MS identification of CXCL7, LBP, TGFβ1 and PDGFRβ as novel biomarkers in human systemic mastocytosis.5
352945312022Identification of CD14 and lipopolysaccharide-binding protein as novel biomarkers for sarcoidosis using proteomics of serum extracellular vesicles.7
353321762022SWATH-MS identification of CXCL7, LBP, TGFβ1 and PDGFRβ as novel biomarkers in human systemic mastocytosis.5
334955022021Association of serum lipopolysaccharide-binding protein level with sensitization to food allergens in children.4
349210592021A Genetic Variation of Lipopolysaccharide Binding Protein Affects the Inflammatory Response and Is Associated with Improved Outcome during Sepsis.2
349487682021Shift Work Predicts Increases in Lipopolysaccharide-Binding Protein, Interleukin-10, and Leukocyte Counts in a Cross-Sectional Study of Healthy Volunteers Carrying Low-Grade Systemic Inflammation.8

Citation

Dessen P

LBP (lipopolysaccharide binding protein)

Atlas Genet Cytogenet Oncol Haematol. 2008-10-01

Online version: http://atlasgeneticsoncology.org/gene/50443/lbp