AQP5 (aquaporin 5)

2008-10-01  

Identity

HGNC
AQP5
LOCATION
12q13.12
LOCUSID
362
ALIAS
AQP-5,PPKB

Other Information

Locus ID:

NCBI: 362
MIM: 600442
HGNC: 638
Ensembl: ENSG00000161798

Variants:

dbSNP: 362
ClinVar: 362
TCGA: ENSG00000161798
COSMIC: AQP5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000161798ENST00000293599P55064

Expression (GTEx)

0
100
200
300
400
500
600
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Salivary secretionKEGGko04970
Salivary secretionKEGGhsa04970
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Aquaporin-mediated transportREACTOMER-HSA-445717
Passive transport by AquaporinsREACTOMER-HSA-432047

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
380472982024Involvement of aquaporin 5 and Na-K-2Cl cotransporter 1 in the pathogenesis of primary focal hyperhidrosis: evidence from the primary sweat gland cell culture.0
380472982024Involvement of aquaporin 5 and Na-K-2Cl cotransporter 1 in the pathogenesis of primary focal hyperhidrosis: evidence from the primary sweat gland cell culture.0
364688422023The cell polarity protein Scribble is downregulated by the water channel aquaporin-5 in breast cancer cells.2
366215352023Involvement of aquaporin 5 in Sjögren's syndrome.9
366458582023AQP5, a second gene at play with CFTR in aquagenic palmoplantar keratoderma.1
367060902023Aquaporin 5 (AQP5) expression in breast cancer and its clinicopathological characteristics.2
367668102023The Role of Aquaporin 5 (AQP5) in Lung Adenocarcinoma: A Review Article.0
364688422023The cell polarity protein Scribble is downregulated by the water channel aquaporin-5 in breast cancer cells.2
366215352023Involvement of aquaporin 5 in Sjögren's syndrome.9
366458582023AQP5, a second gene at play with CFTR in aquagenic palmoplantar keratoderma.1
367060902023Aquaporin 5 (AQP5) expression in breast cancer and its clinicopathological characteristics.2
367668102023The Role of Aquaporin 5 (AQP5) in Lung Adenocarcinoma: A Review Article.0
344551072022Up-regulation of Aquaporin 5 Defines Spasmolytic Polypeptide-Expressing Metaplasia and Progression to Incomplete Intestinal Metaplasia.19
354559862022Aquaporin-3 and Aquaporin-5 Facilitate Migration and Cell-Cell Adhesion in Pancreatic Cancer by Modulating Cell Biomechanical Properties.8
361779152022Expression of ICOS in the salivary glands of patients with primary Sjogren's syndrome and its molecular mechanism.0

Citation

Dessen P

AQP5 (aquaporin 5)

Atlas Genet Cytogenet Oncol Haematol. 2008-10-01

Online version: http://atlasgeneticsoncology.org/gene/50455