CDCA4 (cell division cycle associated 4)

2008-12-01  

Identity

HGNC
LOCATION
14q32.33
LOCUSID
ALIAS
HEPP,SEI-3/HEPP
FUSION GENES

Other Information

Locus ID:

NCBI: 55038
MIM: 612270
HGNC: 14625
Ensembl: ENSG00000170779

Variants:

dbSNP: 55038
ClinVar: 55038
TCGA: ENSG00000170779
COSMIC: CDCA4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170779ENST00000336219Q9BXL8
ENSG00000170779ENST00000336219A0A024R6P3
ENSG00000170779ENST00000392590Q9BXL8
ENSG00000170779ENST00000392590A0A024R6P3

Expression (GTEx)

0
10
20
30
40
50
60

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
379494192024ALKBH5 promotes the development of lung adenocarcinoma by regulating the polarization of M2 macrophages through CDCA4.1
379494192024ALKBH5 promotes the development of lung adenocarcinoma by regulating the polarization of M2 macrophages through CDCA4.1
367374052023CDCA4 interacts with IGF2BP1 to regulate lung adenocarcinoma proliferation via the PI3K/AKT pathway.2
367374052023CDCA4 interacts with IGF2BP1 to regulate lung adenocarcinoma proliferation via the PI3K/AKT pathway.2
352510072022A Pan-Cancer Analysis of the Oncogenic Role of Cell Division Cycle-Associated Protein 4 (CDCA4) in Human Tumors.18
353780002022STAT1 Mediates the Transcription of CircIFI30 and Promotes the Progression of Triple-Negative Breast Cancer by Up-Regulating CDCA4.4
352510072022A Pan-Cancer Analysis of the Oncogenic Role of Cell Division Cycle-Associated Protein 4 (CDCA4) in Human Tumors.18
353780002022STAT1 Mediates the Transcription of CircIFI30 and Promotes the Progression of Triple-Negative Breast Cancer by Up-Regulating CDCA4.4
328080322021Apelin enhances biological functions in lung cancer A549 cells by downregulating exosomal miR-15a-5p.12
336406032021ELK1-induced upregulation lncRNA LINC02381 accelerates the osteosarcoma tumorigenesis through targeting CDCA4 via sponging miR-503-5p.12
339304992021PCOS follicular fluid derived exosomal miR-424-5p induces granulosa cells senescence by targeting CDCA4 expression.26
347237302021Implications of cell division cycle associated 4 on the Wilm's tumor cells viability via AKT/mTOR signaling pathway.3
347724282021MiR-497-5p down-regulates CDCA4 to restrains lung squamous cell carcinoma progression.6
328080322021Apelin enhances biological functions in lung cancer A549 cells by downregulating exosomal miR-15a-5p.12
336406032021ELK1-induced upregulation lncRNA LINC02381 accelerates the osteosarcoma tumorigenesis through targeting CDCA4 via sponging miR-503-5p.12

Citation

Dessen P

CDCA4 (cell division cycle associated 4)

Atlas Genet Cytogenet Oncol Haematol. 2008-12-01

Online version: http://atlasgeneticsoncology.org/gene/50473/cdca4