Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23129
MIM: 604282
HGNC: 9107
Ensembl: ENSG00000004399
Variants:
dbSNP: 23129
ClinVar: 23129
TCGA: ENSG00000004399
COSMIC: PLXND1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Axon guidance | REACTOME | R-HSA-422475 |
| Semaphorin interactions | REACTOME | R-HSA-373755 |
| Other semaphorin interactions | REACTOME | R-HSA-416700 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35396997 | 2023 | Biallelic alterations in PLXND1 cause common arterial trunk and other cardiac malformations in humans. | 2 |
| 37073425 | 2023 | Downregulation of circ_PLXND1 inhibits tumorigenesis of non-small cell lung carcinoma via miR-1287-5p/ERBB3 axis. | 3 |
| 35396997 | 2023 | Biallelic alterations in PLXND1 cause common arterial trunk and other cardiac malformations in humans. | 2 |
| 37073425 | 2023 | Downregulation of circ_PLXND1 inhibits tumorigenesis of non-small cell lung carcinoma via miR-1287-5p/ERBB3 axis. | 3 |
| 34297034 | 2022 | Identification of plexin D1 on circulating extracellular vesicles as a potential biomarker of polymyositis and dermatomyositis. | 4 |
| 34791216 | 2022 | Association of PLXND1 with a novel subtype of anomalous pulmonary venous return. | 1 |
| 35917012 | 2022 | PLXND1/SEMA3E Promotes Epithelial-Mesenchymal Transition Partly via the PI3K/AKT-Signaling Pathway and Induces Heterogenity in Colorectal Cancer. | 2 |
| 34297034 | 2022 | Identification of plexin D1 on circulating extracellular vesicles as a potential biomarker of polymyositis and dermatomyositis. | 4 |
| 34791216 | 2022 | Association of PLXND1 with a novel subtype of anomalous pulmonary venous return. | 1 |
| 35917012 | 2022 | PLXND1/SEMA3E Promotes Epithelial-Mesenchymal Transition Partly via the PI3K/AKT-Signaling Pathway and Induces Heterogenity in Colorectal Cancer. | 2 |
| 32971928 | 2020 | Semaphorin4A-Plexin D1 Axis Induces Th2 and Th17 While Represses Th1 Skewing in an Autocrine Manner. | 9 |
| 32971928 | 2020 | Semaphorin4A-Plexin D1 Axis Induces Th2 and Th17 While Represses Th1 Skewing in an Autocrine Manner. | 9 |
| 31152824 | 2019 | Divergent roles of Plexin D1 in cancer. | 15 |
| 31152824 | 2019 | Divergent roles of Plexin D1 in cancer. | 15 |
| 28554271 | 2018 | Genetic variants and clinical relevance associated with gestational diabetes mellitus in Chinese women: a case-control study. | 5 |
Citation
Dessen P
PLXND1 (plexin D1)
Atlas Genet Cytogenet Oncol Haematol. 2008-12-01
Online version: http://atlasgeneticsoncology.org/gene/50545/plxnd1
