RAB11FIP1 (RAB11 family interacting protein 1)

2008-12-01  

Identity

HGNC
RAB11FIP1
LOCATION
8p11.23
LOCUSID
80223
ALIAS
NOEL1A,RCP,rab11-FIP1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 80223
MIM: 608737
HGNC: 30265
Ensembl: ENSG00000156675

Variants:

dbSNP: 80223
ClinVar: 80223
TCGA: ENSG00000156675
COSMIC: RAB11FIP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000156675ENST00000287263Q6WKZ4
ENSG00000156675ENST00000330843Q6WKZ4
ENSG00000156675ENST00000522727E7EX40
ENSG00000156675ENST00000524118Q6WKZ4

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
379458152024microRNA-205 represses breast cancer metastasis by perturbing the rab coupling protein [RCP]-mediated integrin β1 recycling on the membrane.0
379458152024microRNA-205 represses breast cancer metastasis by perturbing the rab coupling protein [RCP]-mediated integrin β1 recycling on the membrane.0
363543402022Rab11-FIP1C Is Dispensable for HIV-1 Replication in Primary CD4(+) T Cells, but Its Role Is Cell Type Dependent in Immortalized Human T-Cell Lines.2
363543402022Rab11-FIP1C Is Dispensable for HIV-1 Replication in Primary CD4(+) T Cells, but Its Role Is Cell Type Dependent in Immortalized Human T-Cell Lines.2
341523902021Rab11FIP1 maintains Rab35 at the intercellular bridge to promote actin removal and abscission.5
346388062021Rab11-FIP1 and Rab11-FIP5 Regulate pIgR/pIgA Transcytosis through TRIM21-Mediated Polyubiquitination.4
341523902021Rab11FIP1 maintains Rab35 at the intercellular bridge to promote actin removal and abscission.5
346388062021Rab11-FIP1 and Rab11-FIP5 Regulate pIgR/pIgA Transcytosis through TRIM21-Mediated Polyubiquitination.4
326402142020Mutant p53 Drives Cancer Metastasis via RCP-Mediated Hsp90α Secretion.26
327280682020Zeb1 for RCP-induced oral cancer cell invasion and its suppression by resveratrol.12
328609532020Thrombin-activated PAR1 membrane expression is regulated by Rab11a-RCP complex dissociation.0
326402142020Mutant p53 Drives Cancer Metastasis via RCP-Mediated Hsp90α Secretion.26
327280682020Zeb1 for RCP-induced oral cancer cell invasion and its suppression by resveratrol.12
328609532020Thrombin-activated PAR1 membrane expression is regulated by Rab11a-RCP complex dissociation.0
299153782018Rab11 activity and PtdIns(3)P turnover removes recycling cargo from endosomes.46

Citation

Dessen P

RAB11FIP1 (RAB11 family interacting protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2008-12-01

Online version: http://atlasgeneticsoncology.org/gene/50552