Identity
HGNC
LOCATION
12p11.21
LOCUSID
ALIAS
DLP1,DRP1,DVLP,DYMPLE,EMPF,EMPF1,HDYNIV,OPA5
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10059
MIM: 603850
HGNC: 2973
Ensembl: ENSG00000087470
Variants:
dbSNP: 10059
ClinVar: 10059
TCGA: ENSG00000087470
COSMIC: DNM1L
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38019609 | 2024 | Effects of phosphorylation on Drp1 activation by its receptors, actin, and cardiolipin. | 3 |
| 38340166 | 2024 | Enhanced T cell immune activity mediated by Drp1 promotes the efficacy of PD-1 inhibitors in treating lung cancer. | 0 |
| 38459420 | 2024 | Circ_0098823 binding with IGF2BP3 regulates DNM1L stability to promote metastasis of hepatocellular carcinoma via mitochondrial fission. | 2 |
| 38504290 | 2024 | A partial Drp1 knockout improves autophagy flux independent of mitochondrial function. | 0 |
| 38578426 | 2024 | Intertwined relationship of dynamin-related protein 1, mitochondrial metabolism and circadian rhythm. | 2 |
| 38587461 | 2024 | GTPBP8 modulates mitochondrial fission through a Drp1-dependent process. | 0 |
| 38724987 | 2024 | MAP4K4 exacerbates cardiac microvascular injury in diabetes by facilitating S-nitrosylation modification of Drp1. | 1 |
| 38760979 | 2024 | Serine 39 in the GTP-binding domain of Drp1 is involved in shaping mitochondrial morphology. | 0 |
| 38763207 | 2024 | MCU inhibition protects against intestinal ischemia‒reperfusion by inhibiting Drp1-dependent mitochondrial fission. | 0 |
| 38019609 | 2024 | Effects of phosphorylation on Drp1 activation by its receptors, actin, and cardiolipin. | 3 |
| 38340166 | 2024 | Enhanced T cell immune activity mediated by Drp1 promotes the efficacy of PD-1 inhibitors in treating lung cancer. | 0 |
| 38459420 | 2024 | Circ_0098823 binding with IGF2BP3 regulates DNM1L stability to promote metastasis of hepatocellular carcinoma via mitochondrial fission. | 2 |
| 38504290 | 2024 | A partial Drp1 knockout improves autophagy flux independent of mitochondrial function. | 0 |
| 38578426 | 2024 | Intertwined relationship of dynamin-related protein 1, mitochondrial metabolism and circadian rhythm. | 2 |
| 38587461 | 2024 | GTPBP8 modulates mitochondrial fission through a Drp1-dependent process. | 0 |
Citation
Dessen P
DNM1L (dynamin 1 like)
Atlas Genet Cytogenet Oncol Haematol. 2008-12-01
Online version: http://atlasgeneticsoncology.org/gene/50558/dnm1l
