EGFL7 (EGF like domain multiple 7)

2008-12-01  

Identity

HGNC
EGFL7
LOCATION
9q34.3
LOCUSID
51162
ALIAS
NEU1,VE-STATIN,ZNEU1

Other Information

Locus ID:

NCBI: 51162
MIM: 608582
HGNC: 20594
Ensembl: ENSG00000172889

Variants:

dbSNP: 51162
ClinVar: 51162
TCGA: ENSG00000172889
COSMIC: EGFL7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172889ENST00000308874Q9UHF1
ENSG00000172889ENST00000308874A0A024R8F5
ENSG00000172889ENST00000371698Q9UHF1
ENSG00000172889ENST00000371698A0A024R8F5
ENSG00000172889ENST00000371699Q9UHF1
ENSG00000172889ENST00000371699A0A024R8F5
ENSG00000172889ENST00000406555Q9UHF1
ENSG00000172889ENST00000406555A0A024R8F5
ENSG00000172889ENST00000492862R4GMT3

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
372099012023Epidermal growth factor-like 7 is a novel therapeutic target in mantle cell lymphoma.0
379572492023Low EGFL7 expression is associated with high lymph node spread and invasion of lymphatic vessels in colorectal cancer.0
372099012023Epidermal growth factor-like 7 is a novel therapeutic target in mantle cell lymphoma.0
379572492023Low EGFL7 expression is associated with high lymph node spread and invasion of lymphatic vessels in colorectal cancer.0
346359682022Relation among EGFL7, ITGB3, and KLF2 and their clinical implication in multiple myeloma patients: a prospective study.1
347386252022EGF repeats of epidermal growth factor‑like domain 7 promote endothelial cell activation and tumor escape from the immune system.0
356300042022Impact of Activation of EGFL7 within Microenvironment of High Grade Ovarian Serous Carcinoma on Infiltration of CD4+ and CD8+ Lymphocytes.1
363094842022EGFL7 drives the evolution of resistance to EGFR inhibitors in lung cancer by activating NOTCH signaling.3
346359682022Relation among EGFL7, ITGB3, and KLF2 and their clinical implication in multiple myeloma patients: a prospective study.1
347386252022EGF repeats of epidermal growth factor‑like domain 7 promote endothelial cell activation and tumor escape from the immune system.0
356300042022Impact of Activation of EGFL7 within Microenvironment of High Grade Ovarian Serous Carcinoma on Infiltration of CD4+ and CD8+ Lymphocytes.1
363094842022EGFL7 drives the evolution of resistance to EGFR inhibitors in lung cancer by activating NOTCH signaling.3
327840032021Treatment of pregnancies complicated by intrauterine growth restriction with nitric oxide donors increases placental expression of Epidermal Growth Factor-Like Domain 7 and improves fetal growth: A pilot study.7
331916402021Evaluation of the prognostic potential of EGFL7 in pilocytic astrocytomas.2
340800272021An increase in elastogenic components in the placental villi of women with chronic venous disease during pregnancy is associated with decreased EGFL7 expression level.5

Citation

Dessen P

EGFL7 (EGF like domain multiple 7)

Atlas Genet Cytogenet Oncol Haematol. 2008-12-01

Online version: http://atlasgeneticsoncology.org/gene/50572/img/cancer-prone-explorer/gene-explorer/