Identity
HGNC
LOCATION
8p11.23
LOCUSID
ALIAS
BRFU,TFIIIB50
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55290
MIM: 607013
HGNC: 17298
Ensembl: ENSG00000104221
Variants:
dbSNP: 55290
ClinVar: 55290
TCGA: ENSG00000104221
COSMIC: BRF2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000104221 | ENST00000220659 | Q9HAW0 |
| ENSG00000104221 | ENST00000520601 | E5RGX1 |
| ENSG00000104221 | ENST00000521170 | E5RGF6 |
| ENSG00000104221 | ENST00000522539 | E5RGF6 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33453679 | 2021 | TFIIB-related factor 2 regulates glucose-regulated protein 78 expression in acquired middle ear cholesteatoma. | 1 |
| 33453679 | 2021 | TFIIB-related factor 2 regulates glucose-regulated protein 78 expression in acquired middle ear cholesteatoma. | 1 |
| 31964245 | 2020 | MicroRNA-425-5p Inhibits Lung Cancer Cell Growth in Vitro and in Vivo by Downregulating TFIIB-Related Factor 2. | 1 |
| 32705258 | 2020 | Silencing of BRF2 inhibits the growth and metastasis of lung cancer cells. | 3 |
| 33176745 | 2020 | A meta-analysis of BRF2 as a prognostic biomarker in invasive breast carcinoma. | 6 |
| 31964245 | 2020 | MicroRNA-425-5p Inhibits Lung Cancer Cell Growth in Vitro and in Vivo by Downregulating TFIIB-Related Factor 2. | 1 |
| 32705258 | 2020 | Silencing of BRF2 inhibits the growth and metastasis of lung cancer cells. | 3 |
| 33176745 | 2020 | A meta-analysis of BRF2 as a prognostic biomarker in invasive breast carcinoma. | 6 |
| 30618167 | 2019 | Long noncoding RNA MNX1-AS1 contributes to lung cancer progression through the miR-527/BRF2 pathway. | 33 |
| 30618167 | 2019 | Long noncoding RNA MNX1-AS1 contributes to lung cancer progression through the miR-527/BRF2 pathway. | 33 |
| 28854119 | 2018 | New tricks for an old dog: Brf2-dependent RNA Polymerase III transcription in oxidative stress and cancer. | 3 |
| 29025258 | 2018 | MicroRNA-373 Inhibits Cell Proliferation and Invasion via Targeting BRF2 in Human Non-small Cell Lung Cancer A549 Cell Line. | 15 |
| 28854119 | 2018 | New tricks for an old dog: Brf2-dependent RNA Polymerase III transcription in oxidative stress and cancer. | 3 |
| 29025258 | 2018 | MicroRNA-373 Inhibits Cell Proliferation and Invasion via Targeting BRF2 in Human Non-small Cell Lung Cancer A549 Cell Line. | 15 |
| 28743884 | 2017 | Molecular mechanisms of Bdp1 in TFIIIB assembly and RNA polymerase III transcription initiation. | 23 |
Citation
Dessen P
BRF2 (BRF2 RNA polymerase III transcription initiation factor subunit)
Atlas Genet Cytogenet Oncol Haematol. 2008-12-01
Online version: http://atlasgeneticsoncology.org/gene/50599/brf2
