TEAD1 (TEA domain transcription factor 1)

2009-01-01  

Identity

HGNC
TEAD1
LOCATION
11p15.3
LOCUSID
7003
ALIAS
AA,NTEF-1,REF1,TCF-13,TCF13,TEAD-1,TEF-1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 7003
MIM: 189967
HGNC: 11714
Ensembl: ENSG00000187079

Variants:

dbSNP: 7003
ClinVar: 7003
TCGA: ENSG00000187079
COSMIC: TEAD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000187079ENST00000334310P28347
ENSG00000187079ENST00000526600E9PKB7
ENSG00000187079ENST00000527376H0YCZ6
ENSG00000187079ENST00000527575H0YEJ9
ENSG00000187079ENST00000527636H0YE88

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Hippo signaling pathwayKEGGhsa04390
Hippo signaling pathwayKEGGko04390
Hippo signalingKEGGhsa_M00683
Hippo signalingKEGGM00683
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
YAP1- and WWTR1 (TAZ)-stimulated gene expressionREACTOMER-HSA-2032785
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)REACTOMER-HSA-400206
PPARA activates gene expressionREACTOMER-HSA-1989781
Hippo signaling pathway -multiple speciesKEGGko04392
Hippo signaling pathway -multiple speciesKEGGhsa04392

References

Pubmed IDYearTitleCitations
379174102024Mechanosignaling YAP/TAZ-TEAD Axis Regulates the Immunomodulatory Properties of Mesenchymal Stem Cells.0
382257502024SUMOylation of TEAD1 Modulates the Mechanism of Pathological Cardiac Hypertrophy.1
386701072024TM7SF3 controls TEAD1 splicing to prevent MASH-induced liver fibrosis.0
387406372024MKLN1-AS promotes pancreatic cancer progression as a crucial downstream mediator of HIF-1α through miR-185-5p/TEAD1 pathway.0
379174102024Mechanosignaling YAP/TAZ-TEAD Axis Regulates the Immunomodulatory Properties of Mesenchymal Stem Cells.0
382257502024SUMOylation of TEAD1 Modulates the Mechanism of Pathological Cardiac Hypertrophy.1
386701072024TM7SF3 controls TEAD1 splicing to prevent MASH-induced liver fibrosis.0
387406372024MKLN1-AS promotes pancreatic cancer progression as a crucial downstream mediator of HIF-1α through miR-185-5p/TEAD1 pathway.0
366576372023VGLL4-TEAD1 promotes vascular smooth muscle cell differentiation from human pluripotent stem cells via TET2.2
370585582023TEAD1 trapping by the Q353R-Lamin A/C causes dilated cardiomyopathy.3
375747232023Distinct response of adipocyte progenitors to glucocorticoids determines visceral obesity via the TEAD1-miR-27b-PRDM16 axis.0
375782372023Nuclear proinflammatory cytokine S100A9 enhances expression of human papillomavirus oncogenes via transcription factor TEAD1.1
377525882023Long non-coding HOXA-AS3 contributes to osteosarcoma progression through the miR-1286/TEAD1 axis.3
366576372023VGLL4-TEAD1 promotes vascular smooth muscle cell differentiation from human pluripotent stem cells via TET2.2
370585582023TEAD1 trapping by the Q353R-Lamin A/C causes dilated cardiomyopathy.3

Citation

Dessen P

TEAD1 (TEA domain transcription factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2009-01-01

Online version: http://atlasgeneticsoncology.org/gene/50607