EMB (embigin)

2009-01-01  

Identity

HGNC
LOCATION
5q11.1
LOCUSID
ALIAS
GP70
FUSION GENES

Other Information

Locus ID:

NCBI: 133418
MIM: 615669
HGNC: 30465
Ensembl: ENSG00000170571

Variants:

dbSNP: 133418
ClinVar: 133418
TCGA: ENSG00000170571
COSMIC: EMB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170571ENST00000303221Q6PCB8
ENSG00000170571ENST00000508934D6RDX7
ENSG00000170571ENST00000514111Q6PCB8

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsREACTOMER-HSA-425366
Proton-coupled monocarboxylate transportREACTOMER-HSA-433692

References

Pubmed IDYearTitleCitations
322131692020Rare and common variants analysis of the EMB gene in patients with schizophrenia.3
322131692020Rare and common variants analysis of the EMB gene in patients with schizophrenia.3
304466212019Membrane-anchored carbonic anhydrase IV interacts with monocarboxylate transporters via their chaperones CD147 and GP70.17
304466212019Membrane-anchored carbonic anhydrase IV interacts with monocarboxylate transporters via their chaperones CD147 and GP70.17
257739082016Embigin is overexpressed in pancreatic ductal adenocarcinoma and regulates cell motility through epithelial to mesenchymal transition via the TGF-β pathway.12
257739082016Embigin is overexpressed in pancreatic ductal adenocarcinoma and regulates cell motility through epithelial to mesenchymal transition via the TGF-β pathway.12
260907212015Embigin, regulated by HOXC8, plays a suppressive role in breast tumorigenesis.13
260907212015Embigin, regulated by HOXC8, plays a suppressive role in breast tumorigenesis.13
217873882011Monocarboxylate transporter 4 (MCT4) and CD147 overexpression is associated with poor prognosis in prostate cancer.80
217873882011Monocarboxylate transporter 4 (MCT4) and CD147 overexpression is associated with poor prognosis in prostate cancer.80
29638221988A teratocarcinoma glycoprotein carrying a developmentally regulated carbohydrate marker is a member of the immunoglobulin gene superfamily.12
29638221988A teratocarcinoma glycoprotein carrying a developmentally regulated carbohydrate marker is a member of the immunoglobulin gene superfamily.12

Citation

Dessen P

EMB (embigin)

Atlas Genet Cytogenet Oncol Haematol. 2009-01-01

Online version: http://atlasgeneticsoncology.org/gene/50617/img/gene-fusions/teaching-explorer/