CSH1 (chorionic somatomammotropin hormone 1)

2009-01-01  

Identity

HGNC
LOCATION
17q23.3
LOCUSID
ALIAS
CS-1,CSA,CSMT,GHB3,PL,hCS-1,hCS-A
FUSION GENES

Other Information

Locus ID:

NCBI: 1442
MIM: 150200
HGNC: 2440
Ensembl: ENSG00000136488

Variants:

dbSNP: 1442
ClinVar: 1442
TCGA: ENSG00000136488
COSMIC: CSH1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136488ENST00000316193P0DML2
ENSG00000136488ENST00000316193A8K6C2
ENSG00000136488ENST00000329882A6NFB4
ENSG00000136488ENST00000453363B1A4H2
ENSG00000136488ENST00000610991A0A087WUG6

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Neuroactive ligand-receptor interactionKEGGko04080
Jak-STAT signaling pathwayKEGGko04630
Neuroactive ligand-receptor interactionKEGGhsa04080
Jak-STAT signaling pathwayKEGGhsa04630
PI3K-Akt signaling pathwayKEGGhsa04151
PI3K-Akt signaling pathwayKEGGko04151
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Growth hormone receptor signalingREACTOMER-HSA-982772
Prolactin receptor signalingREACTOMER-HSA-1170546

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
346010012021Plasmin generates vasoinhibin-like peptides by cleaving prolactin and placental lactogen.8
346010012021Plasmin generates vasoinhibin-like peptides by cleaving prolactin and placental lactogen.8
325009482020Obesity and regulation of human placental lactogen production in pregnancy.10
325009482020Obesity and regulation of human placental lactogen production in pregnancy.10
290684192017FGF-2b and h-PL Transform Duct and Non-Endocrine Human Pancreatic Cells into Endocrine Insulin Secreting Cells by Modulating Differentiating Genes.7
290684192017FGF-2b and h-PL Transform Duct and Non-Endocrine Human Pancreatic Cells into Endocrine Insulin Secreting Cells by Modulating Differentiating Genes.7
237448832014Increased levels of cell-free human placental lactogen mRNA at 28-32 gestational weeks in plasma of pregnant women with placenta previa and invasive placenta.7
244085182014Human placental lactogen induces CYP2E1 expression via PI 3-kinase pathway in female human hepatocytes.9
244752732014Placental lactogen is expressed but is not translated into protein in breast cancer.3
237448832014Increased levels of cell-free human placental lactogen mRNA at 28-32 gestational weeks in plasma of pregnant women with placenta previa and invasive placenta.7
244085182014Human placental lactogen induces CYP2E1 expression via PI 3-kinase pathway in female human hepatocytes.9
244752732014Placental lactogen is expressed but is not translated into protein in breast cancer.3
234658802013Growth restricting effects of a single course of antenatal betamethasone treatment and the role of human placental lactogen.13
234658802013Growth restricting effects of a single course of antenatal betamethasone treatment and the role of human placental lactogen.13
223870442012Differential placental expression profile of human Growth Hormone/Chorionic Somatomammotropin genes in pregnancies with pre-eclampsia and gestational diabetes mellitus.14

Citation

Dessen P

CSH1 (chorionic somatomammotropin hormone 1)

Atlas Genet Cytogenet Oncol Haematol. 2009-01-01

Online version: http://atlasgeneticsoncology.org/gene/50632/csh1