Identity
HGNC
LOCATION
12p12.1
LOCUSID
ALIAS
BHLHB3,DEC2,FNSS1,SHARP1,hDEC2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79365
MIM: 606200
HGNC: 16617
Ensembl: ENSG00000123095
Variants:
dbSNP: 79365
ClinVar: 79365
TCGA: ENSG00000123095
COSMIC: BHLHE41
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000123095 | ENST00000242728 | Q9C0J9 |
| ENSG00000123095 | ENST00000242728 | A0A024RAV8 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Circadian rhythm | KEGG | ko04710 |
| Circadian rhythm | KEGG | hsa04710 |
| Circadian Clock | REACTOME | R-HSA-400253 |
| BMAL1:CLOCK,NPAS2 activates circadian gene expression | REACTOME | R-HSA-1368108 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37511489 | 2023 | Approach to Functions of BHLHE41/DEC2 in Non-Small Lung Cancer Development. | 2 |
| 37511489 | 2023 | Approach to Functions of BHLHE41/DEC2 in Non-Small Lung Cancer Development. | 2 |
| 33990215 | 2021 | Inhibition of DEC2 is necessary for exiting cell dormancy in salivary adenoid cystic carcinoma. | 4 |
| 34638690 | 2021 | The Potential Roles of Dec1 and Dec2 in Periodontal Inflammation. | 7 |
| 34768959 | 2021 | BHLHE41/DEC2 Expression Induces Autophagic Cell Death in Lung Cancer Cells and Is Associated with Favorable Prognosis for Patients with Lung Adenocarcinoma. | 4 |
| 33990215 | 2021 | Inhibition of DEC2 is necessary for exiting cell dormancy in salivary adenoid cystic carcinoma. | 4 |
| 34638690 | 2021 | The Potential Roles of Dec1 and Dec2 in Periodontal Inflammation. | 7 |
| 34768959 | 2021 | BHLHE41/DEC2 Expression Induces Autophagic Cell Death in Lung Cancer Cells and Is Associated with Favorable Prognosis for Patients with Lung Adenocarcinoma. | 4 |
| 32073238 | 2020 | BHLHE41 suppresses MCF-7 cell invasion via MAPK/JNK pathway. | 7 |
| 32521900 | 2020 | MicroRNA-301a inhibits the progression of osteosarcoma by regulating DEC2. | 1 |
| 32858102 | 2020 | ARID1A-dependent permissive chromatin accessibility licenses estrogen-receptor signaling to regulate circadian rhythms genes in endometrial cancer. | 5 |
| 33101542 | 2020 | DEC2 Serves as Potential Tumor Suppressor in Breast Carcinoma. | 3 |
| 33176151 | 2020 | TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41. | 23 |
| 32073238 | 2020 | BHLHE41 suppresses MCF-7 cell invasion via MAPK/JNK pathway. | 7 |
| 32521900 | 2020 | MicroRNA-301a inhibits the progression of osteosarcoma by regulating DEC2. | 1 |
Citation
Dessen P
BHLHE41 (basic helix-loop-helix family member e41)
Atlas Genet Cytogenet Oncol Haematol. 2009-01-01
Online version: http://atlasgeneticsoncology.org/gene/50651/bhlhe41
