SSBP1 (single stranded DNA binding protein 1)

2009-03-01  

Identity

HGNC
LOCATION
7q34
LOCUSID
ALIAS
Mt-SSB,OPA13,SOSS-B1,SSBP,mtSSB
FUSION GENES

Other Information

Locus ID:

NCBI: 6742
MIM: 600439
HGNC: 11317
Ensembl: ENSG00000106028

Variants:

dbSNP: 6742
ClinVar: 6742
TCGA: ENSG00000106028
COSMIC: SSBP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000106028ENST00000265304Q04837
ENSG00000106028ENST00000265304A4D1U3
ENSG00000106028ENST00000463093C9K0U8
ENSG00000106028ENST00000465582Q04837
ENSG00000106028ENST00000465582A4D1U3
ENSG00000106028ENST00000467681E7EUY5
ENSG00000106028ENST00000473783C9J8J0
ENSG00000106028ENST00000481508Q04837
ENSG00000106028ENST00000481508A4D1U3
ENSG00000106028ENST00000484178Q04837
ENSG00000106028ENST00000484178A4D1U3
ENSG00000106028ENST00000498107Q04837
ENSG00000106028ENST00000498107A4D1U3
ENSG00000106028ENST00000612337Q04837
ENSG00000106028ENST00000612337A4D1U3

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
DNA replicationKEGGko03030
Mismatch repairKEGGko03430
Homologous recombinationKEGGko03440
DNA replicationKEGGhsa03030
Mismatch repairKEGGhsa03430
Homologous recombinationKEGGhsa03440
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Mitochondrial biogenesisREACTOMER-HSA-1592230
Transcriptional activation of mitochondrial biogenesisREACTOMER-HSA-2151201

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
352408182022Identification of SSBP1 as a prognostic marker in human lung adenocarcinoma using bioinformatics approaches.0
361809562022Identification of SSBP1 as a ferroptosis-related biomarker of glioblastoma based on a novel mitochondria-related gene risk model and in vitro experiments.8
352408182022Identification of SSBP1 as a prognostic marker in human lung adenocarcinoma using bioinformatics approaches.0
361809562022Identification of SSBP1 as a ferroptosis-related biomarker of glioblastoma based on a novel mitochondria-related gene risk model and in vitro experiments.8
336714002021De Novo Development of mtDNA Deletion Due to Decreased POLG and SSBP1 Expression in Humans.8
338479642021Analysis of Mitochondrial SSB-DNA Complexes and Their Effects on DNA Polymerase γ Activity by Electron Microscopy and Enzymatic Assays.0
338479652021Optical Tweezers to Investigate the Structure and Energetics of Single-Stranded DNA-Binding Protein-DNA Complexes.1
338479682021Stimulation of Variant Forms of the Mitochondrial DNA Helicase Twinkle by the Mitochondrial Single-Stranded DNA-Binding Protein.0
345485402021Characterization of SSBP1-related optic atrophy and foveopathy.4
349050222021SSBP1-Disease Update: Expanding the Genetic and Clinical Spectrum, Reporting Variable Penetrance and Confirming Recessive Inheritance.5
336714002021De Novo Development of mtDNA Deletion Due to Decreased POLG and SSBP1 Expression in Humans.8
338479642021Analysis of Mitochondrial SSB-DNA Complexes and Their Effects on DNA Polymerase γ Activity by Electron Microscopy and Enzymatic Assays.0
338479652021Optical Tweezers to Investigate the Structure and Energetics of Single-Stranded DNA-Binding Protein-DNA Complexes.1
338479682021Stimulation of Variant Forms of the Mitochondrial DNA Helicase Twinkle by the Mitochondrial Single-Stranded DNA-Binding Protein.0
345485402021Characterization of SSBP1-related optic atrophy and foveopathy.4

Citation

Dessen P

SSBP1 (single stranded DNA binding protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2009-03-01

Online version: http://atlasgeneticsoncology.org/gene/50698/gene-fusions/js/lib/gene-fusions-explorer/