Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79831
MIM: 611917
HGNC: 25840
Ensembl: ENSG00000155666
Variants:
dbSNP: 79831
ClinVar: 79831
TCGA: ENSG00000155666
COSMIC: KDM8
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Chromatin organization | REACTOME | R-HSA-4839726 |
| Chromatin modifying enzymes | REACTOME | R-HSA-3247509 |
| HDMs demethylate histones | REACTOME | R-HSA-3214842 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37813845 | 2023 | JMJD5 inhibits lung cancer progression by facilitating EGFR proteasomal degradation. | 1 |
| 37813845 | 2023 | JMJD5 inhibits lung cancer progression by facilitating EGFR proteasomal degradation. | 1 |
| 35176452 | 2022 | Jumonji-C domain-containing protein 5 suppresses proliferation and aerobic glycolysis in pancreatic cancer cells in a c-Myc-dependent manner. | 2 |
| 35176452 | 2022 | Jumonji-C domain-containing protein 5 suppresses proliferation and aerobic glycolysis in pancreatic cancer cells in a c-Myc-dependent manner. | 2 |
| 32678829 | 2020 | Downregulation of Jumonji-C domain-containing protein 5 inhibits proliferation by silibinin in the oral cancer PDTX model. | 7 |
| 32747552 | 2020 | JMJD5 couples with CDK9 to release the paused RNA polymerase II. | 6 |
| 32678829 | 2020 | Downregulation of Jumonji-C domain-containing protein 5 inhibits proliferation by silibinin in the oral cancer PDTX model. | 7 |
| 32747552 | 2020 | JMJD5 couples with CDK9 to release the paused RNA polymerase II. | 6 |
| 30072740 | 2019 | KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC. | 55 |
| 30551455 | 2019 | Down-regulation of JMJD5 suppresses metastasis and induces apoptosis in oral squamous cell carcinoma by regulating p53/NF-κB pathway. | 19 |
| 30072740 | 2019 | KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC. | 55 |
| 30551455 | 2019 | Down-regulation of JMJD5 suppresses metastasis and induces apoptosis in oral squamous cell carcinoma by regulating p53/NF-κB pathway. | 19 |
| 29459673 | 2018 | Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7. | 14 |
| 29563586 | 2018 | JMJD5 is a human arginyl C-3 hydroxylase. | 23 |
| 29459673 | 2018 | Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7. | 14 |
Citation
Dessen P
KDM8 (lysine demethylase 8)
Atlas Genet Cytogenet Oncol Haematol. 2009-03-01
Online version: http://atlasgeneticsoncology.org/gene/50701/kdm8
