VANGL1 (VANGL planar cell polarity protein 1)

2009-03-01  

Identity

HGNC
VANGL1
LOCATION
1p13.1
LOCUSID
81839
ALIAS
KITENIN,LPP2,STB2,STBM2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 81839
MIM: 610132
HGNC: 15512
Ensembl: ENSG00000173218

Variants:

dbSNP: 81839
ClinVar: 81839
TCGA: ENSG00000173218
COSMIC: VANGL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173218ENST00000310260Q8TAA9
ENSG00000173218ENST00000310260A0A024R0E3
ENSG00000173218ENST00000355485Q8TAA9
ENSG00000173218ENST00000355485A0A024R0E3
ENSG00000173218ENST00000369509Q8TAA9
ENSG00000173218ENST00000369509A0A024R0E3
ENSG00000173218ENST00000369510Q8TAA9

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Wnt signaling pathwayKEGGko04310
Wnt signaling pathwayKEGGhsa04310

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
386691832024Core planar cell polarity genes VANGL1 and VANGL2 in predisposition to congenital vertebral malformations.0
386691832024Core planar cell polarity genes VANGL1 and VANGL2 in predisposition to congenital vertebral malformations.0
357130472022Myelomeningocele among Pakistani population.2
357130472022Myelomeningocele among Pakistani population.2
347509552021Knockdown of circular RNA VANGL1 inhibits TGF-β-induced epithelial-mesenchymal transition in melanoma cells by sponging miR-150-5p.9
350286162021Deletions in VANGL1 are a risk factor for antibody-mediated kidney disease.3
347509552021Knockdown of circular RNA VANGL1 inhibits TGF-β-induced epithelial-mesenchymal transition in melanoma cells by sponging miR-150-5p.9
350286162021Deletions in VANGL1 are a risk factor for antibody-mediated kidney disease.3
317586552020Silencing circular RNA VANGL1 inhibits progression of bladder cancer by regulating miR-1184/IGFBP2 axis.19
323562302020Somatic mutations in planar cell polarity genes in neural tissue from human fetuses with neural tube defects.18
332287402020Up-regulation of VANGL1 by IGF2BPs and miR-29b-3p attenuates the detrimental effect of irradiation on lung adenocarcinoma.34
317586552020Silencing circular RNA VANGL1 inhibits progression of bladder cancer by regulating miR-1184/IGFBP2 axis.19
323562302020Somatic mutations in planar cell polarity genes in neural tissue from human fetuses with neural tube defects.18
332287402020Up-regulation of VANGL1 by IGF2BPs and miR-29b-3p attenuates the detrimental effect of irradiation on lung adenocarcinoma.34
301467362019Circular RNA circ-VANGL1 as a competing endogenous RNA contributes to bladder cancer progression by regulating miR-605-3p/VANGL1 pathway.37

Citation

Dessen P

VANGL1 (VANGL planar cell polarity protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2009-03-01

Online version: http://atlasgeneticsoncology.org/gene/50805/teaching-explorer/gene-fusions/js/lib/jquery-3.5.1.min.js