Identity
HGNC
LOCATION
16p12.1
LOCUSID
ALIAS
CAGH26,FAME6,GW1,GW182,TNRC6
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 27327
MIM: 610739
HGNC: 11969
Ensembl: ENSG00000090905
Variants:
dbSNP: 27327
ClinVar: 27327
TCGA: ENSG00000090905
COSMIC: TNRC6A
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443309 | Alcoholism | Disease | ClinicalAnnotation | associated | PD | 32451486 | |
| PA448073 | ethanol | Chemical | ClinicalAnnotation | associated | PD | 32451486 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36495604 | 2023 | MiR-652-3p promotes malignancy and metastasis of cancer cells via inhibiting TNRC6A in hepatocellular carcinoma. | 0 |
| 36719626 | 2023 | LINC01082 Inhibits Non-Small Cell Lung Cancer by Targeting the miR-543/TNRC6A Axis. | 0 |
| 37427791 | 2023 | RNA helicase DDX6 and scaffold protein GW182 in P-bodies promote biogenesis of stress granules. | 6 |
| 37976119 | 2023 | Hypoxic BMSC-derived exosomal miR-652-3p promotes proliferation and metastasis of hepatocarcinoma cancer cells via targeting TNRC6A. | 1 |
| 36495604 | 2023 | MiR-652-3p promotes malignancy and metastasis of cancer cells via inhibiting TNRC6A in hepatocellular carcinoma. | 0 |
| 36719626 | 2023 | LINC01082 Inhibits Non-Small Cell Lung Cancer by Targeting the miR-543/TNRC6A Axis. | 0 |
| 37427791 | 2023 | RNA helicase DDX6 and scaffold protein GW182 in P-bodies promote biogenesis of stress granules. | 6 |
| 37976119 | 2023 | Hypoxic BMSC-derived exosomal miR-652-3p promotes proliferation and metastasis of hepatocarcinoma cancer cells via targeting TNRC6A. | 1 |
| 35822830 | 2022 | N-terminal Ago-binding domain of GW182 contains a tryptophan-rich region that confer binding to the CCR4-NOT complex. | 0 |
| 35822830 | 2022 | N-terminal Ago-binding domain of GW182 contains a tryptophan-rich region that confer binding to the CCR4-NOT complex. | 0 |
| 33040085 | 2021 | DNA analysis of benign adult familial myoclonic epilepsy reveals associations between the pathogenic TTTCA repeat insertion in SAMD12 and the nonpathogenic TTTTA repeat expansion in TNRC6A. | 5 |
| 33668648 | 2021 | Identification of Phosphorylated Amino Acids in Human TNRC6A C-Terminal Region and Their Effects on the Interaction with the CCR4-NOT Complex. | 1 |
| 33962210 | 2021 | Acute necrotizing encephalopathy-linked mutations in Nup358 impair interaction of Nup358 with TNRC6/GW182 and miRNA function. | 6 |
| 34108231 | 2021 | Impact of scaffolding protein TNRC6 paralogs on gene expression and splicing. | 5 |
| 33040085 | 2021 | DNA analysis of benign adult familial myoclonic epilepsy reveals associations between the pathogenic TTTCA repeat insertion in SAMD12 and the nonpathogenic TTTTA repeat expansion in TNRC6A. | 5 |
Citation
Dessen P
TNRC6A (trinucleotide repeat containing adaptor 6A)
Atlas Genet Cytogenet Oncol Haematol. 2009-03-01
Online version: http://atlasgeneticsoncology.org/gene/50817/tnrc6a
