CD5L (CD5 molecule like)

2009-04-01  

Identity

HGNC
CD5L
LOCATION
1q23.1
LOCUSID
922
ALIAS
AIM,API6,CT-2,PRO229,SP-ALPHA,Spalpha,hAIM

Other Information

Locus ID:

NCBI: 922
MIM: 602592
HGNC: 1690
Ensembl: ENSG00000073754

Variants:

dbSNP: 922
ClinVar: 922
TCGA: ENSG00000073754
COSMIC: CD5L

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000073754ENST00000368174O43866

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
500
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
380067112024AIM/CD5L ameliorates autoimmune arthritis by promoting removal of inflammatory DAMPs at the lesions.1
380067112024AIM/CD5L ameliorates autoimmune arthritis by promoting removal of inflammatory DAMPs at the lesions.1
364270042023The comprehensive role of apoptosis inhibitor of macrophage (AIM) in pathological conditions.3
370875802023[CD5L is elevated in the serum of patients with candidemia and promotes disease progression in mouse models].0
371914812023CD5L aggravates rheumatoid arthritis progression via promoting synovial fibroblasts proliferation and activity.1
375923302023Apoptosis inhibitor of macrophage (AIM)/CD5L is involved in the pathogenesis of COPD.1
364270042023The comprehensive role of apoptosis inhibitor of macrophage (AIM) in pathological conditions.3
370875802023[CD5L is elevated in the serum of patients with candidemia and promotes disease progression in mouse models].0
371914812023CD5L aggravates rheumatoid arthritis progression via promoting synovial fibroblasts proliferation and activity.1
375923302023Apoptosis inhibitor of macrophage (AIM)/CD5L is involved in the pathogenesis of COPD.1
352491362022CD5L Secreted by Macrophage on Atherosclerosis Progression Based on Lipid Metabolism Induced Inflammatory Damage.1
353309092022Reduced Plasma Extracellular Vesicle CD5L Content in Patients With Acute-On-Chronic Liver Failure: Interplay With Specialized Pro-Resolving Lipid Mediators.9
352491362022CD5L Secreted by Macrophage on Atherosclerosis Progression Based on Lipid Metabolism Induced Inflammatory Damage.1
353309092022Reduced Plasma Extracellular Vesicle CD5L Content in Patients With Acute-On-Chronic Liver Failure: Interplay With Specialized Pro-Resolving Lipid Mediators.9
341944272021The Role of Renal Macrophage, AIM, and TGF-β1 Expression in Renal Fibrosis Progression in IgAN Patients.17

Citation

Dessen P

CD5L (CD5 molecule like)

Atlas Genet Cytogenet Oncol Haematol. 2009-04-01

Online version: http://atlasgeneticsoncology.org/gene/50837/gene-explorer/img/logo-atlas-4.svg