Identity
HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
CT31,JARID1B,MRT65,PLU-1,PLU1,PPP1R98,PUT1,RBBP2H1A,RBP2-H1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10765
MIM: 605393
HGNC: 18039
Ensembl: ENSG00000117139
Variants:
dbSNP: 10765
ClinVar: 10765
TCGA: ENSG00000117139
COSMIC: KDM5B
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38014925 | 2024 | Lysine demethylase 5B (KDM5B): A key regulator of cancer drug resistance. | 0 |
| 38230606 | 2024 | Histone demethylase KDM5 regulates cardiomyocyte maturation by promoting fatty acid oxidation, oxidative phosphorylation, and myofibrillar organization. | 4 |
| 38287116 | 2024 | Deubiquitinase USP7 stabilizes KDM5B and promotes tumor progression and cisplatin resistance in nasopharyngeal carcinoma through the ZBTB16/TOP2A axis. | 2 |
| 38296629 | 2024 | Histone lysine demethylase KDM5B facilitates proliferation and suppresses apoptosis in human acute myeloid leukemia cells through the miR-140-3p/BCL2 axis. | 0 |
| 38353298 | 2024 | KDM5B promotes metastasis and epithelial-mesenchymal transition via Wnt/β-catenin pathway in squamous cell carcinoma of the head and neck. | 1 |
| 38880187 | 2024 | ETS homologous factor, controlled by lysine-specific demethylase 5B, suppresses clear cell renal cell carcinoma by inducing Filamin-B. | 0 |
| 38014925 | 2024 | Lysine demethylase 5B (KDM5B): A key regulator of cancer drug resistance. | 0 |
| 38230606 | 2024 | Histone demethylase KDM5 regulates cardiomyocyte maturation by promoting fatty acid oxidation, oxidative phosphorylation, and myofibrillar organization. | 4 |
| 38287116 | 2024 | Deubiquitinase USP7 stabilizes KDM5B and promotes tumor progression and cisplatin resistance in nasopharyngeal carcinoma through the ZBTB16/TOP2A axis. | 2 |
| 38296629 | 2024 | Histone lysine demethylase KDM5B facilitates proliferation and suppresses apoptosis in human acute myeloid leukemia cells through the miR-140-3p/BCL2 axis. | 0 |
| 38353298 | 2024 | KDM5B promotes metastasis and epithelial-mesenchymal transition via Wnt/β-catenin pathway in squamous cell carcinoma of the head and neck. | 1 |
| 38880187 | 2024 | ETS homologous factor, controlled by lysine-specific demethylase 5B, suppresses clear cell renal cell carcinoma by inducing Filamin-B. | 0 |
| 36404720 | 2023 | Long Noncoding RNA HOXA-AS2 Facilitates Prostate Cancer Progression by Inhibiting miR-885-5p to Upregulate KDM5B. | 4 |
| 36697763 | 2023 | A truncated and catalytically inactive isoform of KDM5B histone demethylase accumulates in breast cancer cells and regulates H3K4 tri-methylation and gene expression. | 4 |
| 37254514 | 2023 | PLU1 Promotes the Proliferation and Migration of Glioma Cells and Regulates Metabolism. | 1 |
Citation
Dessen P
KDM5B (lysine demethylase 5B)
Atlas Genet Cytogenet Oncol Haematol. 2009-04-01
Online version: http://atlasgeneticsoncology.org/gene/50846/kdm5b
