Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 25798
MIM: 615628
HGNC: 1109
Ensembl: ENSG00000164713
Variants:
dbSNP: 25798
ClinVar: 25798
TCGA: ENSG00000164713
COSMIC: BRI3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000164713 | ENST00000297290 | O95415 |
| ENSG00000164713 | ENST00000491463 | I3L1V6 |
| ENSG00000164713 | ENST00000539286 | F5GXW6 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Neutrophil degranulation | REACTOME | R-HSA-6798695 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32160551 | 2020 | NRBP1-Containing CRL2/CRL4A Regulates Amyloid β Production by Targeting BRI2 and BRI3 for Degradation. | 13 |
| 32160551 | 2020 | NRBP1-Containing CRL2/CRL4A Regulates Amyloid β Production by Targeting BRI2 and BRI3 for Degradation. | 13 |
| 20538055 | 2010 | Analysis of the Wnt/B-catenin/TCF4 pathway using SAGE, genome-wide microarray and promoter analysis: Identification of BRI3 and HSF2 as novel targets. | 12 |
| 20538055 | 2010 | Analysis of the Wnt/B-catenin/TCF4 pathway using SAGE, genome-wide microarray and promoter analysis: Identification of BRI3 and HSF2 as novel targets. | 12 |
| 19366692 | 2009 | BRI3 inhibits amyloid precursor protein processing in a mechanistically distinct manner from its homologue dementia gene BRI2. | 0 |
| 19366692 | 2009 | BRI3 inhibits amyloid precursor protein processing in a mechanistically distinct manner from its homologue dementia gene BRI2. | 0 |
| 18452648 | 2008 | BRI3 associates with SCG10 and attenuates NGF-induced neurite outgrowth in PC12 cells. | 0 |
| 18452648 | 2008 | BRI3 associates with SCG10 and attenuates NGF-induced neurite outgrowth in PC12 cells. | 0 |
| 17390049 | 2007 | A gene signature of 8 genes could identify the risk of recurrence and progression in Dukes' B colon cancer patients. | 27 |
| 17390049 | 2007 | A gene signature of 8 genes could identify the risk of recurrence and progression in Dukes' B colon cancer patients. | 27 |
| 16508092 | 2005 | Crystallization and preliminary X-ray analysis of the GST-fused human Bri3 N-terminal domain. | 1 |
| 16508092 | 2005 | Crystallization and preliminary X-ray analysis of the GST-fused human Bri3 N-terminal domain. | 1 |
Citation
Dessen P
BRI3 (brain protein I3)
Atlas Genet Cytogenet Oncol Haematol. 2009-05-01
Online version: http://atlasgeneticsoncology.org/gene/50886/bri3
