Identity
HGNC
LOCATION
3p22.3
LOCUSID
ALIAS
CKLFSF8,CKLFSF8-V2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 152189
MIM: 607891
HGNC: 19179
Ensembl: ENSG00000170293
Variants:
dbSNP: 152189
ClinVar: 152189
TCGA: ENSG00000170293
COSMIC: CMTM8
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000170293 | ENST00000307526 | Q8IZV2 |
| ENSG00000170293 | ENST00000458535 | Q8IZV2 |
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447197 | Attention Deficit Disorder with Hyperactivity | Disease | ClinicalAnnotation | associated | PD | 29382897 | |
| PA450464 | methylphenidate | Chemical | ClinicalAnnotation | associated | PD | 29382897 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35429970 | 2022 | Identification and validation of EMT-immune-related prognostic biomarkers CDKN2A, CMTM8 and ILK in colon cancer. | 15 |
| 35429970 | 2022 | Identification and validation of EMT-immune-related prognostic biomarkers CDKN2A, CMTM8 and ILK in colon cancer. | 15 |
| 33395025 | 2021 | Influence of CMTM8 polymorphisms on lung cancer susceptibility in the Chinese Han population. | 1 |
| 33978454 | 2021 | Downregulated CMTM8 Correlates with Poor Prognosis in Gastric Cancer Patients. | 8 |
| 34978519 | 2021 | MicroRNA-582-5p promotes triple-negative breast cancer invasion and metastasis by antagonizing CMTM8. | 8 |
| 33395025 | 2021 | Influence of CMTM8 polymorphisms on lung cancer susceptibility in the Chinese Han population. | 1 |
| 33978454 | 2021 | Downregulated CMTM8 Correlates with Poor Prognosis in Gastric Cancer Patients. | 8 |
| 34978519 | 2021 | MicroRNA-582-5p promotes triple-negative breast cancer invasion and metastasis by antagonizing CMTM8. | 8 |
| 32268840 | 2020 | CMTM8 Is a Suppressor of Human Mesenchymal Stem Cell Osteogenic Differentiation and Promoter of Proliferation Via EGFR Signaling. | 3 |
| 32268840 | 2020 | CMTM8 Is a Suppressor of Human Mesenchymal Stem Cell Osteogenic Differentiation and Promoter of Proliferation Via EGFR Signaling. | 3 |
| 26574634 | 2017 | CMTM8 is Frequently Downregulated in Multiple Solid Tumors. | 11 |
| 26574634 | 2017 | CMTM8 is Frequently Downregulated in Multiple Solid Tumors. | 11 |
| 26615421 | 2016 | Functional characterization of the tumor suppressor CMTM8 and its association with prognosis in bladder cancer. | 9 |
| 26615421 | 2016 | Functional characterization of the tumor suppressor CMTM8 and its association with prognosis in bladder cancer. | 9 |
| 26503336 | 2015 | CMTM8 inhibits the carcinogenesis and progression of bladder cancer. | 16 |
Citation
Dessen P
CMTM8 (CKLF like MARVEL transmembrane domain containing 8)
Atlas Genet Cytogenet Oncol Haematol. 2009-05-01
Online version: http://atlasgeneticsoncology.org/gene/50887/cmtm8
