SLC38A4 (solute carrier family 38 member 4)

2009-05-01  

Identity

HGNC
LOCATION
12q13.11
LOCUSID
ALIAS
ATA3,NAT3,PAAT,SNAT4

Other Information

Locus ID:

NCBI: 55089
MIM: 608065
HGNC: 14679
Ensembl: ENSG00000139209

Variants:

dbSNP: 55089
ClinVar: 55089
TCGA: ENSG00000139209
COSMIC: SLC38A4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139209ENST00000266579Q969I6
ENSG00000139209ENST00000266579A0A024R0X7
ENSG00000139209ENST00000447411Q969I6
ENSG00000139209ENST00000447411A0A024R0X7
ENSG00000139209ENST00000546940F8VRD9
ENSG00000139209ENST00000547477F8VQY9
ENSG00000139209ENST00000550670H0YHZ8

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of inorganic cations/anions and amino acids/oligopeptidesREACTOMER-HSA-425393
Amino acid transport across the plasma membraneREACTOMER-HSA-352230

References

Pubmed IDYearTitleCitations
385087452024Platelets Affect the Activity of Amino Acid Transporter SNAT4 in HuH-7 Human Hepatoma Cells.0
385087452024Platelets Affect the Activity of Amino Acid Transporter SNAT4 in HuH-7 Human Hepatoma Cells.0
366138472022SLC38A4 Amino Acid Transporter Expression Is Significantly Lower in Early Preterm Intrauterine Growth Restriction Complicated Placentas.3
366138472022SLC38A4 Amino Acid Transporter Expression Is Significantly Lower in Early Preterm Intrauterine Growth Restriction Complicated Placentas.3
342749452021SLC38A4 functions as a tumour suppressor in hepatocellular carcinoma through modulating Wnt/β-catenin/MYC/HMGCS2 axis.27
342749452021SLC38A4 functions as a tumour suppressor in hepatocellular carcinoma through modulating Wnt/β-catenin/MYC/HMGCS2 axis.27
275875432016Polymorphisms in cancer-related pathway genes and lung cancer.3
275875432016Polymorphisms in cancer-related pathway genes and lung cancer.3
250638482014PAAT, a novel ATPase and trans-regulator of mitochondrial ABC transporters, is critically involved in the maintenance of mitochondrial homeostasis.7
250638482014PAAT, a novel ATPase and trans-regulator of mitochondrial ABC transporters, is critically involved in the maintenance of mitochondrial homeostasis.7
229456942013Association of the polymorphisms 292 C>T and 1304 G>A in the SLC38A4 gene with hyperglycaemia.5
229456942013Association of the polymorphisms 292 C>T and 1304 G>A in the SLC38A4 gene with hyperglycaemia.5
219179172011Membrane topological structure of neutral system N/A amino acid transporter 4 (SNAT4) protein.6
219179172011Membrane topological structure of neutral system N/A amino acid transporter 4 (SNAT4) protein.6
187039942009Amino acid transport systems beta and A in fetal T lymphocytes in intrauterine growth restriction and with tumor necrosis factor-alpha treatment.4

Citation

Dessen P

SLC38A4 (solute carrier family 38 member 4)

Atlas Genet Cytogenet Oncol Haematol. 2009-05-01

Online version: http://atlasgeneticsoncology.org/gene/50890/slc38a4