KRT75 (keratin 75)

2009-05-01 Affiliation

Identity

HGNC

KRT75

LOCATION

12q13.13

LOCUSID

9119

ALIAS

CK-75,K6HF,K75,KB18,PFB,hK6hf

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 9119
MIM: 609025
HGNC: 24431
Ensembl: ENSG00000170454

Variants:

dbSNP: 9119
ClinVar: 9119
TCGA: ENSG00000170454
COSMIC: KRT75

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000170454	ENST00000252245	O95678

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Developmental Biology	REACTOME	R-HSA-1266738
Keratinization	REACTOME	R-HSA-6805567

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
26709044	2016	Keratins as components of the enamel organic matrix.	13
27130144	2016	Cytokeratin 5/6 and P63 immunophenotype of thyroid lymphoepithelial complexes.	2
26709044	2016	Keratins as components of the enamel organic matrix.	13
27130144	2016	Cytokeratin 5/6 and P63 immunophenotype of thyroid lymphoepithelial complexes.	2
25742793	2015	Cytokeratin 5/6 fingerprinting in HER2-positive tumors identifies a poor prognosis and trastuzumab-resistant basal-HER2 subtype of breast cancer.	6
25742793	2015	Cytokeratin 5/6 fingerprinting in HER2-positive tumors identifies a poor prognosis and trastuzumab-resistant basal-HER2 subtype of breast cancer.	6
25063315	2014	Analysis of clinical characteristics and differential diagnosis of the lung biopsy specimens in 99 adenocarcinoma cases and 111 squamous cell carcinoma cases: utility of an immunohistochemical panel containing CK5/6, CK34βE12, p63, CK7 and TTF-1.	11
25347471	2014	Hair keratin mutations in tooth enamel increase dental decay risk.	24
25063315	2014	Analysis of clinical characteristics and differential diagnosis of the lung biopsy specimens in 99 adenocarcinoma cases and 111 squamous cell carcinoma cases: utility of an immunohistochemical panel containing CK5/6, CK34βE12, p63, CK7 and TTF-1.	11
25347471	2014	Hair keratin mutations in tooth enamel increase dental decay risk.	24
21427063	2011	Breast carcinoma with brain metastases: clinical analysis and immunoprofile on tissue microarrays.	19
21427063	2011	Breast carcinoma with brain metastases: clinical analysis and immunoprofile on tissue microarrays.	19
19614992	2010	Cytokeratin 75 expression in central, centrifugal, cicatricial alopecia--new observations in normal and diseased hair follicles.	6
19614992	2010	Cytokeratin 75 expression in central, centrifugal, cicatricial alopecia--new observations in normal and diseased hair follicles.	6
19366057	2009	Basal cytokeratin expression in relation to immunohistochemical and clinical characterization in breast cancer patients with triple negative phenotype.	9

Citation

Dessen P

KRT75 (keratin 75)

Atlas Genet Cytogenet Oncol Haematol. 2009-05-01

Online version: http://atlasgeneticsoncology.org/gene/50917