Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1404
MIM: 115435
HGNC: 2380
Ensembl: ENSG00000145681
Variants:
dbSNP: 1404
ClinVar: 1404
TCGA: ENSG00000145681
COSMIC: HAPLN1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Extracellular matrix organization | REACTOME | R-HSA-1474244 |
| ECM proteoglycans | REACTOME | R-HSA-3000178 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38032325 | 2024 | Probing binding and occlusion of substrate in the human creatine transporter-1 by computation and mutagenesis. | 1 |
| 38032325 | 2024 | Probing binding and occlusion of substrate in the human creatine transporter-1 by computation and mutagenesis. | 1 |
| 36737556 | 2023 | Hyaluronan and Proteoglycan Link Protein 1 Activates the BMP4/Smad1/5/8 Signaling Pathway to Promote Osteogenic Differentiation: an Implication in Fracture Healing. | 0 |
| 37647592 | 2023 | HAPLN1 matrikine: a bone marrow homing factor linked to poor outcomes in patients with MM. | 0 |
| 36737556 | 2023 | Hyaluronan and Proteoglycan Link Protein 1 Activates the BMP4/Smad1/5/8 Signaling Pathway to Promote Osteogenic Differentiation: an Implication in Fracture Healing. | 0 |
| 37647592 | 2023 | HAPLN1 matrikine: a bone marrow homing factor linked to poor outcomes in patients with MM. | 0 |
| 35604822 | 2022 | A Hyaluronan and Proteoglycan Link Protein 1 Matrikine: Role of Matrix Metalloproteinase 2 in Multiple Myeloma NF-κB Activation and Drug Resistance. | 7 |
| 35720292 | 2022 | HAPLN1 Affects Cell Viability and Promotes the Pro-Inflammatory Phenotype of Fibroblast-Like Synoviocytes. | 10 |
| 35604822 | 2022 | A Hyaluronan and Proteoglycan Link Protein 1 Matrikine: Role of Matrix Metalloproteinase 2 in Multiple Myeloma NF-κB Activation and Drug Resistance. | 7 |
| 35720292 | 2022 | HAPLN1 Affects Cell Viability and Promotes the Pro-Inflammatory Phenotype of Fibroblast-Like Synoviocytes. | 10 |
| 33064036 | 2020 | A Role for HAPLN1 During Phenotypic Modulation of Human Lung Fibroblasts In Vitro. | 14 |
| 33064036 | 2020 | A Role for HAPLN1 During Phenotypic Modulation of Human Lung Fibroblasts In Vitro. | 14 |
| 30279172 | 2019 | Age-Related Changes in HAPLN1 Increase Lymphatic Permeability and Affect Routes of Melanoma Metastasis. | 78 |
| 30279172 | 2019 | Age-Related Changes in HAPLN1 Increase Lymphatic Permeability and Affect Routes of Melanoma Metastasis. | 78 |
| 29279332 | 2018 | Hyaluronan and proteoglycan link protein 1 (HAPLN1) activates bortezomib-resistant NF-κB activity and increases drug resistance in multiple myeloma. | 27 |
Citation
Dessen P
HAPLN1 (hyaluronan and proteoglycan link protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2009-06-01
Online version: http://atlasgeneticsoncology.org/gene/50945/hapln1
