Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 56848
MIM: 607092
HGNC: 18859
Ensembl: ENSG00000063176
Variants:
dbSNP: 56848
ClinVar: 56848
TCGA: ENSG00000063176
COSMIC: SPHK2
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37898377 | 2024 | Accumulation of sphingosine kinase 2 protein induces malignant transformation in oral keratinocytes associated with stemness, autophagy, senescence, and proliferation. | 0 |
| 38048970 | 2024 | The accumulation of sphingosine kinase 2 disrupts the DNA damage response and promotes resistance to genotoxic agents. | 1 |
| 38487884 | 2024 | YTHDF1-mediated sphingosine kinase 2 upregulation alleviates bupivacaine-induced neurotoxicity via the PI3K/AKT axis. | 0 |
| 37898377 | 2024 | Accumulation of sphingosine kinase 2 protein induces malignant transformation in oral keratinocytes associated with stemness, autophagy, senescence, and proliferation. | 0 |
| 38048970 | 2024 | The accumulation of sphingosine kinase 2 disrupts the DNA damage response and promotes resistance to genotoxic agents. | 1 |
| 38487884 | 2024 | YTHDF1-mediated sphingosine kinase 2 upregulation alleviates bupivacaine-induced neurotoxicity via the PI3K/AKT axis. | 0 |
| 36408724 | 2023 | Sphingosine kinase 2 regulates insulin receptor trafficking in hepatocytes. | 0 |
| 36975444 | 2023 | Inhibition of Sphingosine Kinase 2 Results in PARK2-Mediated Mitophagy and Induces Apoptosis in Multiple Myeloma. | 2 |
| 36408724 | 2023 | Sphingosine kinase 2 regulates insulin receptor trafficking in hepatocytes. | 0 |
| 36975444 | 2023 | Inhibition of Sphingosine Kinase 2 Results in PARK2-Mediated Mitophagy and Induces Apoptosis in Multiple Myeloma. | 2 |
| 35088224 | 2022 | miR-153-3p Attenuates the Development of Gastric Cancer by Suppressing SphK2. | 2 |
| 35394045 | 2022 | Upregulated flotillins and sphingosine kinase 2 derail AXL vesicular traffic to promote epithelial-mesenchymal transition. | 3 |
| 35834271 | 2022 | Loss of sphingosine kinase 2 protects against cisplatin-induced kidney injury. | 3 |
| 36070294 | 2022 | Enzymatic independent role of sphingosine kinase 2 in regulating the expression of type I interferon during influenza A virus infection. | 2 |
| 35088224 | 2022 | miR-153-3p Attenuates the Development of Gastric Cancer by Suppressing SphK2. | 2 |
Citation
Dessen P
SPHK2 (sphingosine kinase 2)
Atlas Genet Cytogenet Oncol Haematol. 2009-06-01
Online version: http://atlasgeneticsoncology.org/gene/50985/sphk2
