RBP4 (retinol binding protein 4)

2009-06-01  

Identity

HGNC
RBP4
LOCATION
10q23.33
LOCUSID
5950
ALIAS
MCOPCB10,RDCCAS
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 5950
MIM: 180250
HGNC: 9922
Ensembl: ENSG00000138207

Variants:

dbSNP: 5950
ClinVar: 5950
TCGA: ENSG00000138207
COSMIC: RBP4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138207ENST00000371464P02753
ENSG00000138207ENST00000371467P02753
ENSG00000138207ENST00000371469Q5VY30
ENSG00000138207ENST00000629763Q5VY30

Expression (GTEx)

0
500
1000
1500
2000
2500
3000
3500
4000
4500
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
DiseaseREACTOMER-HSA-1643685
Diseases of signal transductionREACTOMER-HSA-5663202
Diseases associated with visual transductionREACTOMER-HSA-2474795
Retinoid cycle disease eventsREACTOMER-HSA-2453864
Signal TransductionREACTOMER-HSA-162582
Visual phototransductionREACTOMER-HSA-2187338
Retinoid metabolism and transportREACTOMER-HSA-975634
The canonical retinoid cycle in rods (twilight vision)REACTOMER-HSA-2453902
MetabolismREACTOMER-HSA-1430728
Metabolism of vitamins and cofactorsREACTOMER-HSA-196854
Retinoid metabolism disease eventsREACTOMER-HSA-6809583
Metabolism of fat-soluble vitaminsREACTOMER-HSA-6806667

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
369877362024The association between retinol-binding protein 4 and risk of type 2 diabetes: A systematic review and meta-analysis.0
378587462024Are variants of the RBP4 gene associated with serum retinol-binding protein 4 concentrations and carotid intima-media thickness values in women with obesity?0
386713842024Retinol and retinol binding protein 4 levels and COVID-19: a Mendelian randomization study.0
369877362024The association between retinol-binding protein 4 and risk of type 2 diabetes: A systematic review and meta-analysis.0
378587462024Are variants of the RBP4 gene associated with serum retinol-binding protein 4 concentrations and carotid intima-media thickness values in women with obesity?0
386713842024Retinol and retinol binding protein 4 levels and COVID-19: a Mendelian randomization study.0
363735602023The effect of dietary carbohydrate restriction and aerobic exercise on retinol binding protein 4 (RBP4) and fatty acid binding protein 5 (FABP5) in middle-aged men with metabolic syndrome.0
366703872023The relationship between NAFLD and retinol-binding protein 4 - an updated systematic review and meta-analysis.1
371006002023Longitudinal Change of Plasma Retinol-Binding Protein 4 and its Relation to Neurological-Function Recovery, Relapse, and Death in Acute Ischemic Stroke Patients.0
375120892023Visfatin and Retinol Binding Protein-4 in Young-Onset Type 2 Diabetes Mellitus.0
375868362023Clinical, genetic and biochemical signatures of RBP4-related ocular malformations.0
375872502023Targeting Retinol-Binding Protein 4 (RBP4) in the Management of Cardiometabolic Diseases.0
381718132023Does Retinol-Binding Protein 4 (holo- and apo-RBP4) Increase or Remain Constant in Sera from Patients with Hypothyroidism?0
363735602023The effect of dietary carbohydrate restriction and aerobic exercise on retinol binding protein 4 (RBP4) and fatty acid binding protein 5 (FABP5) in middle-aged men with metabolic syndrome.0
366703872023The relationship between NAFLD and retinol-binding protein 4 - an updated systematic review and meta-analysis.1

Citation

Dessen P

RBP4 (retinol binding protein 4)

Atlas Genet Cytogenet Oncol Haematol. 2009-06-01

Online version: http://atlasgeneticsoncology.org/gene/50989