Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2762
MIM: 602884
HGNC: 4369
Ensembl: ENSG00000112699
Variants:
dbSNP: 2762
ClinVar: 2762
TCGA: ENSG00000112699
COSMIC: GMDS
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000112699 | ENST00000380815 | O60547 |
| ENSG00000112699 | ENST00000530927 | O60547 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31375564 | 2019 | Structural and functional analysis of parameters governing tankyrase-1 interaction with telomeric repeat-binding factor 1 and GDP-mannose 4,6-dehydratase. | 13 |
| 31375564 | 2019 | Structural and functional analysis of parameters governing tankyrase-1 interaction with telomeric repeat-binding factor 1 and GDP-mannose 4,6-dehydratase. | 13 |
| 29843634 | 2018 | GMDS knockdown impairs cell proliferation and survival in human lung adenocarcinoma. | 14 |
| 29843634 | 2018 | GMDS knockdown impairs cell proliferation and survival in human lung adenocarcinoma. | 14 |
| 26382291 | 2016 | Disruptions in a cluster of computationally identified enhancers near FOXC1 and GMDS may influence brain development. | 6 |
| 26382291 | 2016 | Disruptions in a cluster of computationally identified enhancers near FOXC1 and GMDS may influence brain development. | 6 |
| 25173105 | 2014 | Common variants near ABCA1, AFAP1 and GMDS confer risk of primary open-angle glaucoma. | 104 |
| 25173105 | 2014 | Common variants near ABCA1, AFAP1 and GMDS confer risk of primary open-angle glaucoma. | 104 |
| 23730929 | 2013 | FX enzyme and GDP-L-Fuc transporter expression in colorectal cancer. | 9 |
| 23922970 | 2013 | Mutation of GDP-mannose-4,6-dehydratase in colorectal cancer metastasis. | 17 |
| 23730929 | 2013 | FX enzyme and GDP-L-Fuc transporter expression in colorectal cancer. | 9 |
| 23922970 | 2013 | Mutation of GDP-mannose-4,6-dehydratase in colorectal cancer metastasis. | 17 |
| 22645305 | 2012 | GDP-mannose-4,6-dehydratase is a cytosolic partner of tankyrase 1 that inhibits its poly(ADP-ribose) polymerase activity. | 25 |
| 22645305 | 2012 | GDP-mannose-4,6-dehydratase is a cytosolic partner of tankyrase 1 that inhibits its poly(ADP-ribose) polymerase activity. | 25 |
| 22027835 | 2011 | GDP-mannose-4,6-dehydratase (GMDS) deficiency renders colon cancer cells resistant to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor- and CD95-mediated apoptosis by inhibiting complex II formation. | 22 |
Citation
Dessen P
GMDS (GDP-mannose 4,6-dehydratase)
Atlas Genet Cytogenet Oncol Haematol. 2009-08-01
Online version: http://atlasgeneticsoncology.org/gene/51014/gmds
