DCAF6 (DDB1 and CUL4 associated factor 6)

2009-08-01  

Identity

HGNC
DCAF6
LOCATION
1q24.2
LOCUSID
55827
ALIAS
1200006M05Rik,ARCAP,IQWD1,MSTP055,NRIP,PC326
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55827
MIM: 610494
HGNC: 30002
Ensembl: ENSG00000143164

Variants:

dbSNP: 55827
ClinVar: 55827
TCGA: ENSG00000143164
COSMIC: DCAF6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143164ENST00000312263Q58WW2
ENSG00000143164ENST00000367840Q58WW2
ENSG00000143164ENST00000367843Q58WW2
ENSG00000143164ENST00000432587Q58WW2
ENSG00000143164ENST00000470721F2Z305

Expression (GTEx)

0
50
100
150
200
250
300
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
381635712024Identification of circular RNA-Dcaf6 as a therapeutic target for optic nerve crush-induced RGC degeneration.0
381635712024Identification of circular RNA-Dcaf6 as a therapeutic target for optic nerve crush-induced RGC degeneration.0
366889592023The CRL4(DCAF6) E3 ligase ubiquitinates CtBP1/2 to induce apoptotic signalling and promote intervertebral disc degeneration.4
366889592023The CRL4(DCAF6) E3 ligase ubiquitinates CtBP1/2 to induce apoptotic signalling and promote intervertebral disc degeneration.4
337730962021Autoantibody of NRIP, a novel AChR-interacting protein, plays a detrimental role in myasthenia gravis.2
337730962021Autoantibody of NRIP, a novel AChR-interacting protein, plays a detrimental role in myasthenia gravis.2
326682862020Circ_DCAF6 potentiates cell stemness and growth in breast cancer through GLI1-Hedgehog pathway.12
326682862020Circ_DCAF6 potentiates cell stemness and growth in breast cancer through GLI1-Hedgehog pathway.12
312262662019Enhanced expression of circular RNA circ-DCAF6 predicts adverse prognosis and promotes cell progression via sponging miR-1231 and miR-1256 in gastric cancer.21
312262662019Enhanced expression of circular RNA circ-DCAF6 predicts adverse prognosis and promotes cell progression via sponging miR-1231 and miR-1256 in gastric cancer.21
242221172013Identification of androgen-responsive microRNAs and androgen-related genes in breast cancer.14
242221172013Identification of androgen-responsive microRNAs and androgen-related genes in breast cancer.14
221776992012NRIP enhances HPV gene expression via interaction with either GR or E2.3
221776992012NRIP enhances HPV gene expression via interaction with either GR or E2.3
190646102009Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation.16

Citation

Dessen P

DCAF6 (DDB1 and CUL4 associated factor 6)

Atlas Genet Cytogenet Oncol Haematol. 2009-08-01

Online version: http://atlasgeneticsoncology.org/gene/51028/css/lib/deep-insight-explorer/haematological-explorer/