Identity
HGNC
LOCATION
21q22.3
LOCUSID
ALIAS
IFI-78K,IFI78,MX,MxA,lncMX1-215
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4599
MIM: 147150
HGNC: 7532
Ensembl: ENSG00000157601
Variants:
dbSNP: 4599
ClinVar: 4599
TCGA: ENSG00000157601
COSMIC: MX1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37586842 | 2024 | Increased expression of human antiviral protein MxA in FUS proteinopathy in amyotrophic lateral sclerosis. | 1 |
| 38054738 | 2024 | Host factor MxA restricts Dabie bandavirus infection by targeting the viral NP protein to inhibit NP-RdRp interaction and ribonucleoprotein activity. | 2 |
| 38372203 | 2024 | Myxovirus resistance protein A (MxA) expression in myositides: Sarcoplasmic expression is common in both dermatomyositis and lupus myositis. | 0 |
| 38429664 | 2024 | Polymorphisms of IFN signaling genes and FOXP4 influence the severity of COVID-19. | 0 |
| 38607029 | 2024 | Oral Antiviral Defense: Saliva- and Beverage-like Hypotonicity Dynamically Regulate Formation of Membraneless Biomolecular Condensates of Antiviral Human MxA in Oral Epithelial Cells. | 0 |
| 37586842 | 2024 | Increased expression of human antiviral protein MxA in FUS proteinopathy in amyotrophic lateral sclerosis. | 1 |
| 38054738 | 2024 | Host factor MxA restricts Dabie bandavirus infection by targeting the viral NP protein to inhibit NP-RdRp interaction and ribonucleoprotein activity. | 2 |
| 38372203 | 2024 | Myxovirus resistance protein A (MxA) expression in myositides: Sarcoplasmic expression is common in both dermatomyositis and lupus myositis. | 0 |
| 38429664 | 2024 | Polymorphisms of IFN signaling genes and FOXP4 influence the severity of COVID-19. | 0 |
| 38607029 | 2024 | Oral Antiviral Defense: Saliva- and Beverage-like Hypotonicity Dynamically Regulate Formation of Membraneless Biomolecular Condensates of Antiviral Human MxA in Oral Epithelial Cells. | 0 |
| 36436557 | 2023 | An evolutionarily conserved N-terminal leucine is essential for MX1 GTPase antiviral activity against different families of RNA viruses. | 4 |
| 36743306 | 2023 | Polymorphisms of the MxA and MxB genes are associated with biochemical indices and viral subtypes in Yunnan HCV patients. | 0 |
| 37506491 | 2023 | Genome-wide DNA methylation analysis implicates enrichment of interferon pathway in African American patients with Systemic Lupus Erythematosus and European Americans with lupus nephritis. | 0 |
| 37596622 | 2023 | Influenza a virus regulates interferon signaling and its associated genes; MxA and STAT3 by cellular miR-141 to ensure viral replication. | 3 |
| 36436557 | 2023 | An evolutionarily conserved N-terminal leucine is essential for MX1 GTPase antiviral activity against different families of RNA viruses. | 4 |
Citation
Dessen P
MX1 (MX dynamin like GTPase 1)
Atlas Genet Cytogenet Oncol Haematol. 2009-08-01
Online version: http://atlasgeneticsoncology.org/gene/51031/mx1
