Identity
HGNC
LOCATION
6q21
LOCUSID
ALIAS
APG5,APG5-LIKE,APG5L,ASP,SCAR25,hAPG5
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9474
MIM: 604261
HGNC: 589
Ensembl: ENSG00000057663
Variants:
dbSNP: 9474
ClinVar: 9474
TCGA: ENSG00000057663
COSMIC: ATG5
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10004 | adalimumab | Chemical | ClinicalAnnotation | associated | PD | 27096233 | |
| PA446116 | Inflammatory Bowel Diseases | Disease | ClinicalAnnotation | associated | PD | 27096233 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37991129 | 2024 | Association of ATG16L1 and ATG5 gene polymorphisms with susceptibility to hepatitis B virus infection and progression to HCC in central China. | 0 |
| 38009708 | 2024 | Autophagy related gene 5 polymorphism rs17587319 (C/G) in asthmatic patients in North Indian population. | 0 |
| 38305285 | 2024 | MIR222HG/LIN28B/ATG5 Axis Drives M2 Macrophage Polarization and Proliferation of Hepatocellular Carcinoma Cells. | 0 |
| 38511768 | 2024 | Serum autophagy-related gene 5 level in stroke patients: correlation with CD4+ T cells and cognition impairment during a 3-year follow-up. | 0 |
| 38530706 | 2024 | Autophagy-related 5 in acute ischemic stroke: Variation and linkage with neurofunction, and survival. | 0 |
| 38747016 | 2024 | Autophagy-related protein 5 (ATG5) interacts with bone marrow stromal cell antigen 2 (BST2) to stimulate HBV replication through antagonizing the antiviral activity of BST2. | 0 |
| 37991129 | 2024 | Association of ATG16L1 and ATG5 gene polymorphisms with susceptibility to hepatitis B virus infection and progression to HCC in central China. | 0 |
| 38009708 | 2024 | Autophagy related gene 5 polymorphism rs17587319 (C/G) in asthmatic patients in North Indian population. | 0 |
| 38305285 | 2024 | MIR222HG/LIN28B/ATG5 Axis Drives M2 Macrophage Polarization and Proliferation of Hepatocellular Carcinoma Cells. | 0 |
| 38511768 | 2024 | Serum autophagy-related gene 5 level in stroke patients: correlation with CD4+ T cells and cognition impairment during a 3-year follow-up. | 0 |
| 38530706 | 2024 | Autophagy-related 5 in acute ischemic stroke: Variation and linkage with neurofunction, and survival. | 0 |
| 38747016 | 2024 | Autophagy-related protein 5 (ATG5) interacts with bone marrow stromal cell antigen 2 (BST2) to stimulate HBV replication through antagonizing the antiviral activity of BST2. | 0 |
| 36805797 | 2023 | Autophagy impairment in patients with obstructive sleep apnea modulates intermittent hypoxia-induced oxidative stress and cell apoptosis via hypermethylation of the ATG5 gene promoter region. | 3 |
| 36912305 | 2023 | Diagnostic Value of ATG5, Apo-Lipoprotein B-48, Thyroid Hormones, and Homocysteine in Patients with Alzheimer's Disease. | 1 |
| 37054706 | 2023 | ATG5 provides host protection acting as a switch in the atg8ylation cascade between autophagy and secretion. | 8 |
Citation
Dessen P
ATG5 (autophagy related 5)
Atlas Genet Cytogenet Oncol Haematol. 2009-08-01
Online version: http://atlasgeneticsoncology.org/gene/51040/atg5
