SCAI (suppressor of cancer cell invasion)

2009-08-01  

Identity

HGNC
SCAI
LOCATION
9q33.3
LOCUSID
286205
ALIAS
C9orf126,NET40
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 286205
HGNC: 26709
Ensembl: ENSG00000173611

Variants:

dbSNP: 286205
ClinVar: 286205
TCGA: ENSG00000173611
COSMIC: SCAI

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173611ENST00000336505Q8N9R8
ENSG00000173611ENST00000373549Q8N9R8
ENSG00000173611ENST00000467917H7C4U2
ENSG00000173611ENST00000477186Q3SXZ0
ENSG00000173611ENST00000494102H7C5A3

Expression (GTEx)

0
1
2
3
4
5
6
7
8
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
RHO GTPase EffectorsREACTOMER-HSA-195258
RHO GTPases Activate ForminsREACTOMER-HSA-5663220

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
370476772023Bridging Gaps in HDR Improvement: The Role of MAD2L2, SCAI, and SCR7.2
377434422023Hsa_circ_0052611 and mir-767-5p guide the warburg effect, migration, and invasion of BRCA cells through modulating SCAI.0
370476772023Bridging Gaps in HDR Improvement: The Role of MAD2L2, SCAI, and SCR7.2
377434422023Hsa_circ_0052611 and mir-767-5p guide the warburg effect, migration, and invasion of BRCA cells through modulating SCAI.0
318518592021Mir-5100 Mediates Proliferation, Migration and Invasion of Oral Squamous Cell Carcinoma Cells Via Targeting SCAI.13
345975962021The Protexin complex counters resection on stalled forks to promote homologous recombination and crosslink repair.11
318518592021Mir-5100 Mediates Proliferation, Migration and Invasion of Oral Squamous Cell Carcinoma Cells Via Targeting SCAI.13
345975962021The Protexin complex counters resection on stalled forks to promote homologous recombination and crosslink repair.11
331037232020miR-371b-5p promotes cell proliferation, migration and invasion in non-small cell lung cancer via SCAI.6
333278892020Inhibition of Microrna-766-5p Attenuates the Development of Cervical Cancer Through Regulating SCAI.5
331037232020miR-371b-5p promotes cell proliferation, migration and invasion in non-small cell lung cancer via SCAI.6
333278892020Inhibition of Microrna-766-5p Attenuates the Development of Cervical Cancer Through Regulating SCAI.5
301809202019Exosomal miR-1228 From Cancer-Associated Fibroblasts Promotes Cell Migration and Invasion of Osteosarcoma by Directly Targeting SCAI.51
305514952019MicroRNA-1270 modulates papillary thyroid cancer cell development by regulating SCAI.21
307201722019MicroRNA-625-3p promotes cell migration of oral squamous cell carcinoma by regulating SCAI expression.5

Citation

Dessen P

SCAI (suppressor of cancer cell invasion)

Atlas Genet Cytogenet Oncol Haematol. 2009-08-01

Online version: http://atlasgeneticsoncology.org/gene/51042