Identity
HGNC
LOCATION
22q13.33
LOCUSID
ALIAS
AM2,dJ579N16.4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79924
MIM: 608682
HGNC: 28898
Ensembl: ENSG00000128165
Variants:
dbSNP: 79924
ClinVar: 79924
TCGA: ENSG00000128165
COSMIC: ADM2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000128165 | ENST00000395737 | Q7Z4H4 |
| ENSG00000128165 | ENST00000395738 | Q7Z4H4 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38087182 | 2024 | Reduced PATL2 Impairs the Proliferation of Ovarian Granulosa Cells by Decreasing ADM2 Expression in Patients with PCOS. | 1 |
| 38087182 | 2024 | Reduced PATL2 Impairs the Proliferation of Ovarian Granulosa Cells by Decreasing ADM2 Expression in Patients with PCOS. | 1 |
| 37146967 | 2023 | Adrenomedullin 2/intermedin is a slow off-rate, long-acting endogenous agonist of the adrenomedullin(2) G protein-coupled receptor. | 2 |
| 37879153 | 2023 | Intermedin alleviates diabetic vascular calcification by inhibiting GLUT1 through activation of the cAMP/PKA signaling pathway. | 0 |
| 37146967 | 2023 | Adrenomedullin 2/intermedin is a slow off-rate, long-acting endogenous agonist of the adrenomedullin(2) G protein-coupled receptor. | 2 |
| 37879153 | 2023 | Intermedin alleviates diabetic vascular calcification by inhibiting GLUT1 through activation of the cAMP/PKA signaling pathway. | 0 |
| 35896852 | 2022 | Intermedin (adrenomedullin 2) promotes breast cancer metastasis via Src/c-Myc-mediated ribosome production and protein translation. | 3 |
| 35896852 | 2022 | Intermedin (adrenomedullin 2) promotes breast cancer metastasis via Src/c-Myc-mediated ribosome production and protein translation. | 3 |
| 32997116 | 2021 | Altered expression of ADM and ADM2 by hypoxia regulates migration of trophoblast and HLA-G expression†. | 6 |
| 33436794 | 2021 | Intermedin facilitates hepatocellular carcinoma cell survival and invasion via ERK1/2-EGR1/DDIT3 signaling cascade. | 6 |
| 33535178 | 2021 | Inhibition of Notch1-mediated inflammation by intermedin protects against abdominal aortic aneurysm via PI3K/Akt signaling pathway. | 8 |
| 34163006 | 2021 | CGRP, adrenomedullin and adrenomedullin 2 display endogenous GPCR agonist bias in primary human cardiovascular cells. | 15 |
| 34434487 | 2021 | Study on Protection of Human Umbilical Vein Endothelial Cells from Amiodarone-Induced Damage by Intermedin through Activation of Wnt/β-Catenin Signaling Pathway. | 4 |
| 34437633 | 2021 | CRIF1 deficiency suppresses endothelial cell migration via upregulation of RhoGDI2. | 3 |
| 32997116 | 2021 | Altered expression of ADM and ADM2 by hypoxia regulates migration of trophoblast and HLA-G expression†. | 6 |
Citation
Dessen P
ADM2 (adrenomedullin 2)
Atlas Genet Cytogenet Oncol Haematol. 2009-08-01
Online version: http://atlasgeneticsoncology.org/gene/51044/adm2
